Nature Search

Social rank modulates methamphetamine-seeking in dominant and subordinate male rodents via distinct dopaminergic pathways

Social status mediates individual differences in methamphetamine-seeking by modulating dopaminergic pathways. In subordinate rodents, the mesolimbic pathway is stronger, and the mesocortical pathway is weaker, whereas dominant rodents show the opposite pattern.

Xiaofei Deng
Wei Xu
Yingjie Zhu
Research12 May 2025
Nature Neuroscience

Volume: 28, P: 1268-1279
Projectome-based characterization of hypothalamic peptidergic neurons in male mice

This study maps the single-axon projections of 7,180 hypothalamic peptidergic neurons in male mice and uncovers extensive collateralization, topographic target innervation and modular intra-hypothalamic organization.

Zhuolei Jiao
Taosha Gao
Xiaohong Xu
Research26 Mar 2025
Nature Neuroscience

Volume: 28, P: 1073-1088
A pangenome reference of 36 Chinese populations

A study reports data from the first phase of the Chinese Pangenome Consortium including 116 de novo assemblies from 58 core samples representing 36 minority Chinese ethnic groups.

Yang Gao
Xiaofei Yang
Shuhua Xu
ResearchOpen Access14 Jun 2023
Nature

Volume: 619, P: 112-121
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis

Xiaofei Huang
Mengru Xie
Lili Chen
ResearchOpen Access23 May 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-18
A DNA phosphorothioation pathway via adenylated intermediate modulates Tdp machinery

An, Tan and colleagues reveal an unusual DNA phosphorothioation Tdp system, where TdpC adenylates DNA backbone for sulfur incorporation and TdpAB provides anti-phage immunity. The sensitivity of TdpAB to hydrophobicity of sulfur enables self–non-self discrimination.

Tianchen An
Qian Tan
Shi Chen
Research16 Jan 2025
Nature Chemical Biology

P: 1-11
Scalable miniature on-chip Fourier transform spectrometer for Raman spectroscopy

We present the demonstration of Raman spectroscopy using a SiN photonics chip spectrometer. This spectrometer will contribute significantly to wearable devices for non-invasive detection, forensic analysis, and space exploration.

Sarp Kerman
Xiao Luo
Chang Chen
ResearchOpen Access30 May 2025
Light: Science & Applications

Volume: 14, P: 1-14
HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance

Zhao et al. report that the Z compartment protein HERD-1 regulates transgenerational epigenetic inheritance in Caenorhabditis elegans at least in part by preventing the mixing of germ granule condensates.

Changfeng Zhao
Shiyu Cai
Gang Wan
Research01 Oct 2024
Nature Cell Biology

Volume: 26, P: 1958-1970
Superconductivity in an infinite-layer nickelate superlattice

So far infinite-layer nickelates have only been observed to superconduct in single-thin-film form. Here, the authors demonstrate superconductivity in [(Nd_0.8Sr_0.2NiO₂)₈/(SrTiO₃)₂]₁₀ superlattices.

Wen Xiao
Zhan Yang
Zhaoliang Liao
ResearchOpen Access25 Nov 2024
Nature Communications

Volume: 15, P: 1-9
Predicting peak particle velocity in pre-splitting of gas-producing devices using improved particle swarm optimization algorithm

Yawen Cao
Rui Ma
Qixiang Gao
ResearchOpen Access21 Apr 2025
Scientific Reports

Volume: 15, P: 1-17
Influenza virus uses mGluR2 as an endocytic receptor to enter cells

Influenza virus uses metabotropic glutamate receptor 2 (mGluR2) as an endocytic receptor to enter cells through clathrin-mediated endocytosis.

Zixin Ni
Jinliang Wang
Zhigao Bu
ResearchOpen Access07 Jun 2024
Nature Microbiology

Volume: 9, P: 1764-1777
Integration of metabolomics and transcriptomics analyses reveals the effects of nano-selenium on pak choi

Yanyan Wang
Peiheng Sun
Xiaofei Li
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
Zona incerta mediates early life isoflurane-induced fear memory deficits

Jing Sun
Xiaofei Deng
Yingjie Zhu
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations

α-ketoglutarate is an intermediate of the Krebs Cycle that was recently reported to extend lifespan in C.Elegans. Here, the authors show that administration of α-ketoglutarate to mice reduces age-related bone loss, by ameliorating senescence of bone-marrow derived mesenchymal stem cells.

Yuan Wang
Peng Deng
Quan Yuan
ResearchOpen Access05 Nov 2020
Nature Communications

Volume: 11, P: 1-14
The Farm Animal Genotype–Tissue Expression (FarmGTEx) Project

The FarmGTEx Project aims to understand genetic control of gene activity under diverse biological and environmental contexts in domestic animals, providing a foundation for improving animal precision breeding, adaptation and human health.

Lingzhao Fang
Jinyan Teng
Curtis P. Van Tassell
Reviews17 Mar 2025
Nature Genetics

Volume: 57, P: 786-796
Genomic insight into domestication of rubber tree

Understanding the genetic basis of rubber tree domestication is critical for improving natural rubber production. Here, the authors assemble the genome of the rubber tree clone CATAS8-79 and conduct population and genetic association analyses to reveal the function of phytosulfokine in regulating number of laticifer rings.

Jinquan Chao
Shaohua Wu
Wei-Min Tian
ResearchOpen Access02 Aug 2023
Nature Communications

Volume: 14, P: 1-13
Primary decidual zone formation requires Scribble for pregnancy success in mice

The scaffold protein Scribble (Scrib) has roles in PCP and tight junction formation. Here the authors show that during embryo implantation in mouse, Scrib is needed to form the avascular primary decidual zone by transforming stromal cells into an epithelial cell-like barrier around the crypt, protecting the embryo from harmful infiltrations.

Jia Yuan
Shizu Aikawa
Sudhansu K. Dey
ResearchOpen Access28 Nov 2019
Nature Communications

Volume: 10, P: 1-10
Reward and aversion processing by input-defined parallel nucleus accumbens circuits in mice

The nucleus accumbens (NAc) is involved in mediating reward seeking and negative valence. Here, the authors present evidence for afferent-specific circuitry of the NAc in the control of reward and aversion via two distinct pathway.

Kuikui Zhou
Hua Xu
Yingjie Zhu
ResearchOpen Access21 Oct 2022
Nature Communications

Volume: 13, P: 1-12
The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex

The mode of action of the biological Dnd antiphage defence system to cleave foreign DNA was not known. Now the activities of Dnd protein complexes are revealed, and a mechanism to discriminate between self-DNA and invading DNA is proposed.

Dan Wu
Yaqian Tang
Shi Chen
Research08 Dec 2022
Nature Catalysis

Volume: 5, P: 1131-1144
Improved adaptive regularization for simulated annealing inversion of transient electromagnetic

Xiang Tang
Shangbin Liu
Huaifeng Sun
ResearchOpen Access04 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Comparative genomic analysis of esophageal squamous cell carcinoma between Asian and Caucasian patient populations

Esophageal squamous cell carcinoma (ESCC) exhibits differences in incidence and survival patterns among races. Here, analysis of Chinese and TCGA ESCC patients reveals that Asian patients exhibit higher TP53, EP300 and NFE2L2 mutational frequencies, and mutated CSMD3 associates with better prognosis.

Jiaying Deng
Hu Chen
Kuaile Zhao
ResearchOpen Access16 Nov 2017
Nature Communications

Volume: 8, P: 1-9
Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas

Despite lung adenocarcinoma having a high global mortality, the genetic mutations present in Asian patients are uncharacterized. Here the authors use genomic and transcriptomic analysis to identify thirteen significantly affected genes, including RHPN2, GLI3, MRC2, TP53 and IQGAP3.

Kui Wu
Xin Zhang
Jianxing He
ResearchOpen Access09 Dec 2015
Nature Communications

Volume: 6, P: 1-13
Risk factors for totally implantable access ports-associated thrombosis in pediatric oncology patients

Yingxia Lan
Liuhong Wu
Ruiqing Cai
ResearchOpen Access02 Mar 2023
Scientific Reports

Volume: 13, P: 1-7
A chromosome-level genome assembly of Mylabris sibirica Fischer von Waldheim, 1823 (Coleoptera, Meloidae)

Chenhui Shen
Guofeng Yang
Xiaohong Yan
ResearchOpen Access14 Feb 2025
Scientific Data

Volume: 12, P: 1-9
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer

Although autophagy has been linked to tumourigenesis, it is unclear how genomic alterations affect autophagy selectivity in tumours. Here, the authors establish a pipeline that integrates computational and experimental approaches to show that altered autophagy selectivity is frequent in cancer cells and link glycogen autophagy with tumourigenesis.

Zhu Han
Weizhi Zhang
Da Jia
ResearchOpen Access31 May 2021
Nature Communications

Volume: 12, P: 1-18
Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation

Embryo implantation initiates the interaction of the blastocyst with the uterus and occurs within a specialised crypt formed by uterine epithelial cells. Here, using 3D imaging techniques of wild type and mutant uteri, the authors show that crypt formation occurs with preexisting glands of the uterus, opening communication between glands and the implanting embryo.

Jia Yuan
Wenbo Deng
Sudhansu. K. Dey
ResearchOpen Access09 Feb 2018
Nature Communications

Volume: 9, P: 1-13
Single-neuron projectome of mouse prefrontal cortex

The authors reconstructed the individual projectomes of 6,357 mouse prefrontal cortical projection neurons, revealing projectome-defined neuron subtypes and organizing principles of axon projections and correspondence with transcriptomes.

Le Gao
Sang Liu
Jun Yan
Research31 Mar 2022
Nature Neuroscience

Volume: 25, P: 515-529
Design, modeling, and manufacturing of high strain composites for space deployable structures

Xiaofei Ma and colleagues provide a review of high-strain composite materials and their use in deployable space structures. The review contributes a broad overview of the field and discusses important design considerations for high-strain composite structures including manufacturing, viscoelasticity, and material selection.

Xiaofei Ma
Ning An
Qilong Jia
ReviewsOpen Access10 Jun 2024
Communications Engineering

Volume: 3, P: 1-18
Ultrafast photonics of two dimensional AuTe₂Se_4/3 in fiber lasers

Two dimensional materials can exhibit unique optical properties, making them interesting for new photonic devices and laser sources. Here, the strong optical nonlinearity of AuTe₂Se_4/3 is exploited to achieve a femtosecond infra-red laser with high stability.

Wenjun Liu
Mengli Liu
Zhiyi Wei
ResearchOpen Access21 Jan 2020
Communications Physics

Volume: 3, P: 1-6
ΔNp63α promotes radioresistance in esophageal squamous cell carcinoma through the PLEC-KEAP1-NRF2 feedback loop

Jin Tao
Mian Mao
Hu Chen
ResearchOpen Access05 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-12
The underlying mechanisms of family function on anxiety among nurses during the public health emergency

Xinru Liu
Wei Dong
Tianya Hou
ResearchOpen Access27 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
A deep learning-based system for automatic detection of emesis with high accuracy in Suncus murinus

The Automatic Emesis Detection (AED) tool uses deep learning to quantify emesis in Suncus murinus with high accuracy, reducing human error and enhancing efficiency, offering potential for preclinical research and drug development.

Zengbing Lu
Yimeng Qiao
John A. Rudd
ResearchOpen Access10 Feb 2025
Communications Biology

Volume: 8, P: 1-11
Identification of an intraocular microbiota

Yuhua Deng
Xiaofei Ge
Lai Wei
ResearchOpen Access09 Mar 2021
Cell Discovery

Volume: 7, P: 1-12
BRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK signaling

Shunkang Wu
Yuelin Deng
Hsiang-Ying Lee
ResearchOpen Access02 Dec 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-15
Author Correction: Identification of an intraocular microbiota

Yuhua Deng
Xiaofei Ge
Lai Wei
Amendments and CorrectionsOpen Access15 May 2024
Cell Discovery

Volume: 10, P: 1
Author Correction: Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases

Liuting Zeng
Kailin Yang
Lingyun Sun
Amendments and CorrectionsOpen Access21 Oct 2024
Cell Death & Disease

Volume: 15, P: 1
High-brightness betatron emission from the interaction of a sub picosecond laser pulse with pre-ionized low-density polymer foam for ICF research

Mikhail Gyrdymov
Jakub Cikhardt
Olga N. Rosmej
ResearchOpen Access26 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD

Xiaofei Wang
Ao Hu
Lilin Ye
ResearchOpen Access05 Apr 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-13
Response of nitric and nitrous oxide fluxes to N fertilizer application in greenhouse vegetable cropping systems in southeast China

Yaojun Zhang
Feng Lin
Jianwen Zou
ResearchOpen Access05 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases

Liuting Zeng
Kailin Yang
Lingyun Sun
ReviewsOpen Access04 Jul 2024
Cell Death & Disease

Volume: 15, P: 1-33
Uterine deficiency of high-mobility group box-1 (HMGB1) protein causes implantation defects and adverse pregnancy outcomes

Shizu Aikawa
Wenbo Deng
Sudhansu K. Dey
Research08 Oct 2019
Cell Death & Differentiation

Volume: 27, P: 1489-1504
A circuit from lateral septum neurotensin neurons to tuberal nucleus controls hedonic feeding

Zijun Chen
Gaowei Chen
Yingjie Zhu
ResearchOpen Access26 Aug 2022
Molecular Psychiatry

Volume: 27, P: 4843-4860
CFTR is a negative regulator of γδ T cell IFN-γ production and antitumor immunity

Yuanyuan Duan
Guangqiang Li
Zhinan Yin
Research15 Jul 2020
Cellular & Molecular Immunology

Volume: 18, P: 1934-1944
First long-term detection of paleo-oceanic signature of dust aerosol at the southern marginal area of the Taklimakan Desert

Qi Zhou
Juan Li
Guoshun Zhuang
ResearchOpen Access30 Apr 2018
Scientific Reports

Volume: 8, P: 1-9
Anaerobic ammonium oxidation and its contribution to nitrogen removal in China’s coastal wetlands

Lijun Hou
Yanling Zheng
Xiaofen Jiang
ResearchOpen Access23 Oct 2015
Scientific Reports

Volume: 5, P: 1-11

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