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Showing 1–50 of 109 results

Advanced filters: Author: Yichang Chen Clear advanced filters

Generalized biological foundation model with unified nucleic acid and protein language

He and colleagues develop LucaOne, a biological foundation model pre-trained on nucleic acid and protein sequences from 169,861 species. It shows an emerging understanding of molecular biology’s central dogma, enhancing bioinformatics analysis and helping explore unknown aspects of molecular biology.

Yong He
Pan Fang
Zhaorong Li
ResearchOpen Access18 Jun 2025
Nature Machine Intelligence

Volume: 7, P: 942-953
Palaeoenvironment and carbon isotope stratigraphy of Upper Proterozoic carbonates of the Yangtze Platform

I. B. Lambert
M. R. Walter
Ma Guogan
Research08 Jan 1987
Nature

Volume: 325, P: 140-142
Lidocaine and risk of postoperative vomiting in children undergoing tonsillectomy: a randomised clinical trial

Yang Hu
Ming-cheng Du
Yuan Gong
ResearchOpen Access26 Aug 2024
Scientific Reports

Volume: 14, P: 1-6
Engineering aptamer-directed phosphatase recruiting chimeras: a strategy for modulating receptor function and overcoming drug resistance

Receptor tyrosine kinases play a key role in the regulation of intracellular signal transduction revealing their potential for targeted therapy. Here this group reports an aptamer-directed phosphatase recruiting chimeras for direct dephosphorylation of tyrosine residues on the receptor targets thereby inhibiting transmission of phosphorylation signals both in vitro/vivo.

Zhilan Zhou
Yichang Liu
Juan Li
ResearchOpen Access25 Apr 2025
Nature Communications

Volume: 16, P: 1-18
Publisher Correction: A chain mediation model reveals the association between parental mediation and smartphone addiction of Chinese adolescents

Yan Chen
Qian Gu
Chuan Ni
Amendments and CorrectionsOpen Access12 Jun 2025
Scientific Reports

Volume: 15, P: 1
A chain mediation model reveals the association between parental mediation and smartphone addiction of Chinese adolescents

Yan Chen
Qian Gu
Chuan Ni
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-13
A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images

An automated deep-learning pipeline for chest-X-ray-image standardization, lesion visualization and disease diagnosis can identify viral pneumonia caused by COVID-19, assess its severity, and discriminate it from other types of pneumonia.

Guangyu Wang
Xiaohong Liu
Tianxin Lin
Research15 Apr 2021
Nature Biomedical Engineering

Volume: 5, P: 509-521
Changes in eye axis length and corneal curvature in central China from the perspective of birth year

Lufan Li
Nan Zhang
Min Ke
Research06 Feb 2025
Eye

Volume: 39, P: 1373-1379
Digital technology and service tradability: evidence from patent innovations and knowledge utilization

LEI WANG
Yihan Chen
Geoffrey Hewings
ResearchOpen Access01 Jul 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-18
m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p

Chunming Zhu
Ruiming Li
Kefeng Wang
ResearchOpen Access17 Jun 2025
npj Precision Oncology

Volume: 9, P: 1-17
Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis

Jun Wei
Min Li
Yunhong Zha
ResearchOpen Access13 Dec 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-8
ZD7288 ameliorates long-term cerebral ischemia reperfusion-induced deterioration of spatial memory by regulating the expressions of NMDA receptor subunits in rats

Zhi He
Xiao-Jiao Chu
Bo Zhao
ResearchOpen Access25 May 2025
Scientific Reports

Volume: 15, P: 1-13
Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway

Chengwu Zhang
Yuanhong Zhou
Yalong Yang
ResearchOpen Access27 Feb 2024
Scientific Reports

Volume: 14, P: 1-12
Capture and conversion of CO₂ at ambient conditions by a conjugated microporous polymer

Conjugated microporous polymers are highly flexible materials that may be used for gas storage and catalysis applications. Here, the authors report metal-functionalized conjugated microporous polymers capable of both capturing CO₂and functioning as a heterogeneous catalyst in its conversion to propylene carbonate.

Yong Xie
Ting-Ting Wang
Wei-Qiao Deng
ResearchOpen Access03 Jun 2013
Nature Communications

Volume: 4, P: 1-7
The ER calcium channel Csg2 integrates sphingolipid metabolism with autophagy

Sphingolipids can function as lipid signaling molecules. Here, the authors find that the endoplasmic reticulum calcium channel Csg2 integrates sphingolipid metabolism with autophagy by regulating calcium homeostasis in endoplasmic reticulum.

Shiyan Liu
Mutian Chen
Kefeng Lu
ResearchOpen Access22 Jun 2023
Nature Communications

Volume: 14, P: 1-19
Efficacy study of neuronavigation-assisted stereotactic drilling of urokinase drainage versus craniotomy in the treatment of massive intracerebral haemorrhage in elderly patientsa

Ziwei Yan
Lai Jiang
Xin Huang
ResearchOpen Access03 Sept 2024
Scientific Reports

Volume: 14, P: 1-10
High sodium intake increases interstitial lung disease and pulmonary sarcoidosis based on the Global Burden of Disease study 1999–2019

Zhigang Hu
Yufeng Tian
Xinyu Song
ResearchOpen Access29 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Insights into excitonic behavior in single-atom covalent organic frameworks for efficient photo-Fenton-like pollutant degradation

Emerging organic contaminants (EOCs) are difficult to remove from complex water systems, but photo-Fenton-like reactions offer a promising solution. Here, the authors develop Cu single-atom loaded covalent organic frameworks to reduce excitonic effects and enhancing radical generation thereby improving EOCs degradation.

Chao Zhu
Mingzheng Yang
Yi Shen
ResearchOpen Access17 Jan 2025
Nature Communications

Volume: 16, P: 1-13
A H₂O₂-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging

Fluorescent imaging in the second biological window has advantages for in vivo applications. Here, the authors synthesise a molecular nanoprobe which activates upon binding H₂O₂, generating both strong fluorescent NIR-II emission and ultrasound signal for multi-mode imaging of inflammatory diseases.

Junjie Chen
Longqi Chen
Yanli Zhao
ResearchOpen Access25 Nov 2021
Nature Communications

Volume: 12, P: 1-15
Bearing characteristics and continuous–discontinuous numerical analysis of a pressure grouting pile in a calcareous sand foundation

Qifen Cheng
Jianlin Li
Ge Zhang
ResearchOpen Access24 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Soil carbon emissions and influential factors across various stages of vegetation succession in vegetated concrete

Yakun Xu
Ting Luo
Jiazhen Gao
ResearchOpen Access12 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
A zinc oxide resonant nano-accelerometer with ultra-high sensitivity

The authors report a zinc oxide resonant nano-accelerometer with sensitivity up to 16.818 kHz/g, which is attributed to the nano-resonators using zinc oxide nanowires and the optimized microleverages and push-pull structures.

Pengfei Xu
Dazhi Wang
Yan Cui
ResearchOpen Access31 May 2024
Nature Communications

Volume: 15, P: 1-8
Study on the performance of new cement-based underwater building crack repair materials based on response surface analysis

Ning Wang
Yinger Deng
Lin Chen
ResearchOpen Access27 May 2025
Scientific Reports

Volume: 15, P: 1-22
Evolution of coopetition between real estate enterprises and urban investment construction companies under an agent construction system

Shaoliang Li
Xiazhong Zheng
Xinxin Xue
ResearchOpen Access20 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Research on low carbon welding scheduling based on production process

Rong Hua Meng
Zan Yang Wang
Shao Hua Deng
ResearchOpen Access20 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
Ultrahigh-water-flux desalination on graphdiyne membranes

Membrane desalination is a promising technology for producing freshwater from saline waters. Submicrometre-thick and nanopore-structured graphdiyne membranes on porous Cu hollow fibres accomplish nearly perfect NaCl rejections and ultrahigh water permeabilities.

Huiling Chen
Xing Liu
Gaofeng Zeng
Research04 Sept 2023
Nature Water

Volume: 1, P: 800-807
Geometry engineering of tunneling transistors in transition metal dichalcogenide nanoribbon heterojunctions

By engineering geometric edges in transition metal dichalcogenide nanoribbons, the authors design multifunctional tunneling heterojunctions based on metallic zigzag and semiconducting armchair edges. The tunneling in T-shaped nanoribbons and resonant tunneling in H-shaped nanoribbons exhibit remarkable robustness against variations in width, while remaining tunable through edge geometry modifications

Ye Jiang
Minjiang Dan
Qiao Chen
ResearchOpen Access30 Apr 2025
Communications Physics

Volume: 8, P: 1-9
Clinical characteristics and risk factors in pneumoconiosis patients with asthma

Zhifeng Chen
Yulin Shang
Xudong Xiang
ResearchOpen Access27 Feb 2025
Scientific Reports

Volume: 15, P: 1-8
Ultimate load analysis of casings in slip-working sections of underground gas storage wells

Yuxian He
Haiyun Ma
Xianzhong Yi
ResearchOpen Access29 Apr 2025
Scientific Reports

Volume: 15, P: 1-21
Microstructural changes are coincident with the improvement of clinical symptoms in surgically treated compressed nerve roots

Weifei Wu
Jie Liang
Zong Yang
ResearchOpen Access15 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Non-intrusive load monitoring based on time-enhanced multidimensional feature visualization

Tie Chen
Yimin Yuan
Pingping Yang
ResearchOpen Access08 Feb 2025
Scientific Reports

Volume: 15, P: 1-18
COVID-19 in persons with chronic myeloid leukaemia

Weiming Li
Danyu Wang
Qian Jiang
Research18 May 2020
Leukemia

Volume: 34, P: 1799-1804
Effects of two types of activated carbon on the properties of vegetation concrete and Cynodon dactylon growth

Jiazhen Gao
Daxiang Liu
Wennian Xu
ResearchOpen Access02 Sept 2020
Scientific Reports

Volume: 10, P: 1-12
Neutrophil percentage to albumin ratio predicts cardiovascular and all-cause mortality in diabetes and pre diabetes patients

Hua Ji
Yongqi Wang
Mingwei Chen
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
Nucleus accumbens circuit disinhibits lateral hypothalamus glutamatergic neurons contributing to morphine withdrawal memory in male mice

Lateral hypothalamus (LH) plays an role in drug addiction. Here, authors present evidence for disinhibited LH glutamatergic neurons by neural circuits from nucleus accumbens to contribute to context-induced expression of morphine withdrawal memory.

Huan Sheng
Chao Lei
Ping Zheng
ResearchOpen Access05 Jan 2023
Nature Communications

Volume: 14, P: 1-16
An 18.9 min blue large-amplitude pulsator crossing the ‘Hertzsprung gap’ of hot subdwarfs

Blue large-amplitude pulsators (BLAPs) represent a mysterious class of hot stars pulsating in an unexpectedly extreme way. Here we report the discovery of an unusual BLAP at a short-lived phase that provides a new path to understand their physical origins.

Jie Lin
Chengyuan Wu
Xinghan Zhang
Research29 Sept 2022
Nature Astronomy

Volume: 7, P: 223-233
Method for detecting cracks in retaining walls based on improved YOLOv5s

Yanhai Wang
Chenxin Guo
Huafeng Deng
ResearchOpen Access20 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
Expression of TCF7L2 in midbrain Vglut2-positive neurons

Huihui Qi
Li Luo
Yichang Jia
Research24 May 2023
Molecular Psychiatry

Volume: 28, P: 1397
Acyl-CoA thioesterase 8 induces gemcitabine resistance via regulation of lipid metabolism and antiferroptotic activity in pancreatic ductal adenocarcinoma

Bo-rui Li
Ting Wang
Xiao-wu Xu
ResearchOpen Access12 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1742-1756
Numerical investigation on the penetration process of steel casings in riprap environment of estuarine mudflats

Weishun Zhao
Zipeng Qin
Yan Tian
ResearchOpen Access07 Mar 2025
Scientific Reports

Volume: 15, P: 1-28
Comment on: “Benchmarking the performance of large language models in uveitis: a comparative analysis of ChatGPT-3.5, ChatGPT-4.0, Google Gemini, and Anthropic Claude3”

Xiao Luo
Cheng Tang
Tao Yan
Correspondence26 Feb 2025
Eye

Volume: 39, P: 1432
Phylotype diversity within soil fungal functional groups drives ecosystem stability

The authors link fungal diversity to the stability of terrestrial ecosystem productivity across three global datasets, finding that richness of decomposers and mycorrhizae are positively associated with stability while the richness of plant pathogens is negatively related to stability.

Shengen Liu
Pablo García-Palacios
Manuel Delgado-Baquerizo
Research09 May 2022
Nature Ecology & Evolution

Volume: 6, P: 900-909
Utilizing the real estate investment trusts for portfolio optimisation by application of genetic algorithm

Li XU
Liviu Marian Matac
Codruta-Daniela Pavel
ResearchOpen Access03 Apr 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-11
Author Correction: A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images

Guangyu Wang
Xiaohong Liu
Tianxin Lin
Amendments and Corrections29 Jul 2021
Nature Biomedical Engineering

Volume: 5, P: 943
Pifithrin-μ sensitizes mTOR-activated liver cancer to sorafenib treatment

Jiarui Lv
Yanan Wang
Hongbing Zhang
ResearchOpen Access26 Jan 2025
Cell Death & Disease

Volume: 16, P: 1-14
Multilayer entropy-weighted TOPSIS method and its decision-making in ecological operation during the subsidence period of the Three Gorges Reservoir

Ai Xueshan
Yu Yangxin
Zhang Xiaoke
ResearchOpen Access23 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
Synthetic lumbar MRI can aid in diagnosis and treatment strategies based on self-pix networks

Ke Song
Wendong Zhu
Weifei Wu
ResearchOpen Access02 Sept 2024
Scientific Reports

Volume: 14, P: 1-14
Tool wear prediction based on XGBoost feature selection combined with PSO-BP network

Zhangwen Lin
Yankun Fan
Weiwei Duan
ResearchOpen Access24 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
Compromised Air Quality and Healthcare Safety from Smoking inside Hospitals in Shantou, China

Jun Zeng
Dangui Zhang
William Ba-Thein
ResearchOpen Access28 May 2019
Scientific Reports

Volume: 9, P: 1-8
High-performance Acetone Soluble Tape Transfer Printing Method for Heterogeneous Integration

Jiaqi Zhang
Yichang Wu
Yue Hao
ResearchOpen Access31 Oct 2019
Scientific Reports

Volume: 9, P: 1-7

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