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Scientific Reports (28)
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Showing 1–50 of 75 results

Advanced filters: Author: Yixing Li Clear advanced filters

Oncogenic fusions converge on shared mechanisms in initiating astroblastoma

The molecular mechanisms of astroblastoma development are identified, whereby distinct gene fusions upregulate shared transcriptional networks to disrupt the normal development of ventral telencephalon neural progenitors, which leads to oncogenesis.

Yixing Shi
Qianqian Sun
Yang Yu
Research14 May 2025
Nature

P: 1-11
Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data

Boao Xiao
Min Yang
Yansu Chen
ResearchOpen Access21 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
Increased Prevalence of Severe Fever with Thrombocytopenia Syndrome in Eastern China Clustered with Multiple Genotypes and Reasserted Virus during 2010–2015

Zhifeng Li
Jianli Hu
Changjun Bao
ResearchOpen Access26 Jul 2017
Scientific Reports

Volume: 7, P: 1-9
Effects of short-term PM_2.5 exposure on blood lipids among 197,957 people in eastern China

Qiao Liu
Zhan Wang
Xuhua Mao
ResearchOpen Access18 Mar 2023
Scientific Reports

Volume: 13, P: 1-9
A risk prediction nomogram for resistant hypertension in patients with obstructive sleep apnea

Hongze Lin
Chen Zhou
Taofeng Zhu
ResearchOpen Access13 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Upregulation and biological function of transmembrane protein 119 in osteosarcoma

Zhen-Huan Jiang
Jun Peng
Zhi-Jun Ge
ResearchOpen Access12 May 2017
Experimental & Molecular Medicine

Volume: 49, P: e329
The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA

Chunlan Liu
Wuzhuang Tang
Chong Shen
Research01 Mar 2021
The Pharmacogenomics Journal

Volume: 21, P: 458-466
The highly allo-autopolyploid modern sugarcane genome and very recent allopolyploidization in Saccharum

A haplotype-resolved genome of hybrid sugarcane cultivar XTT22 and population analyses of Saccharum accessions highlight the genome evolution of allopolyploids and provide opportunities for sugarcane breeding.

Jisen Zhang
Yiying Qi
Haibao Tang
Research03 Jan 2025
Nature Genetics

Volume: 57, P: 242-253
Reactive Hyperemia Index in Patients on Maintenance Hemodialysis: Cross-sectional Data from a Cohort Study

Wenjin Liu
Meijuan Meng
Junwei Yang
ResearchOpen Access30 Mar 2017
Scientific Reports

Volume: 7, P: 1-7
A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration

Jiang et al. identify Pax as a key regulator of Drosophila midgut homeostasis. Pax coordinates the Hippo and Notch pathways to control the proliferation and differentiation of intestinal stem cells (ISCs), ensuring homeostasis of midgut.

Dan Jiang
Pengyue Li
Lei Zhang
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-21
The LINK-A lncRNA interacts with PtdIns(3,4,5)P₃ to hyperactivate AKT and confer resistance to AKT inhibitors

Yang and colleagues report that the LINK-A lncRNA binds to the PIP₃ phospholipid, leading to enhanced AKT signalling, tumorigenesis and resistance to AKT inhibitors.

Aifu Lin
Qingsong Hu
Liuqing Yang
Research20 Feb 2017
Nature Cell Biology

Volume: 19, P: 238-251
A ROR1–HER3–lncRNA signalling axis modulates the Hippo–YAP pathway to regulate bone metastasis

Li et al. show that ROR1–HER3 receptor tyrosine kinase signalling in breast cancer cells inhibits the MST1/2 Hippo pathway kinases through a lncRNA termed MAYA. The resulting activation of YAP promotes osteoclast differentiation for bone metastasis.

Chunlai Li
Shouyu Wang
Liuqing Yang
Research23 Jan 2017
Nature Cell Biology

Volume: 19, P: 106-119
Highly stable QLEDs with improved hole injection via quantum dot structure tailoring

The commercialization of light-emitting diodes based on emissive quantum dots (e.g. QLEDs) is hindered by their inherent poor operational lifetime. Using an intelligent energy-level design strategy, Qian et al. demonstrate QLEDs with operational lifetime that meets industrial display standards.

Weiran Cao
Chaoyu Xiang
Lei Qian
ResearchOpen Access04 Jul 2018
Nature Communications

Volume: 9, P: 1-6
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer

Yang and colleagues identify a lncRNA that controls HIF1α signalling to stabilize HIF1α under normoxic conditions, and promotes breast cancer tumorigenesis.

Aifu Lin
Chunlai Li
Liuqing Yang
Research11 Jan 2016
Nature Cell Biology

Volume: 18, P: 213-224
Charge-assisted stabilization of lipid nanoparticles enables inhaled mRNA delivery for mucosal vaccination

The instability of lipid nanoparticles during nebulization hinders inhaled mRNA vaccines. Here, the authors report on a charge-assisted stabilization strategy using a peptide-lipid conjugate to improve lipid nanoparticle stability, enabling mRNA-based mucosal vaccines for SARS-CoV-2 and lung cancer.

Shuai Liu
Yixing Wen
Xueguang Lu
ResearchOpen Access02 Nov 2024
Nature Communications

Volume: 15, P: 1-18
Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function

Mouse models expressing liver apoE in the absence of brain apoE reveal detrimental effects of peripheral apoE4 associated with Alzheimer’s risk on cognition and amyloid pathology through compromising vascular integrity and function.

Chia-Chen Liu
Jing Zhao
Guojun Bu
Research01 Aug 2022
Nature Neuroscience

Volume: 25, P: 1020-1033
High-performance flexible p-type Ce-filled Fe₃CoSb₁₂ skutterudite thin film for medium-to-high-temperature applications

The authors fabricate p-type Fe₃CoSb₁₂-based skutterudite films exhibiting high thermoelectric performance, stability, and flexibility at medium-to-high temperatures, based on preparing custom target materials and pulsed laser deposition techniques.

Dou Li
Xiao-Lei Shi
Zhi-Gang Chen
ResearchOpen Access18 May 2024
Nature Communications

Volume: 15, P: 1-13
Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

Hashimoto’s thyroiditis (HT) is the main cause of hypothyroidism. Here the authors develop a deep learning model for diagnosis of HT on a large multi-site dataset including image and video data.

Qiang Zhang
Sheng Zhang
Xiangchun Li
ResearchOpen Access29 Jun 2022
Nature Communications

Volume: 13, P: 1-8
Machine learning for post-acute pancreatitis diabetes mellitus prediction and personalized treatment recommendations

Jun Zhang
Yingqi Lv
Ling Li
ResearchOpen Access24 Mar 2023
Scientific Reports

Volume: 13, P: 1-10
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may have a role in disease aetiology.

Fang Qiu
Ruqi Tang
Xiong Ma
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-8
A colorimetric sensing method for direct determination of the adsorption capacity of colored cations in adsorbents

Siyang Xing
Congle Li
Jingtao Bi
ResearchOpen Access26 Nov 2024
npj Clean Water

Volume: 7, P: 1-7
High expression of MAGE-A9 correlates with unfavorable survival in hepatocellular carcinoma

Xuefeng Gu
Maoying Fu
Jin Zhu
ResearchOpen Access15 Oct 2014
Scientific Reports

Volume: 4, P: 1-7
Effects of intrathecal 6-hydroxydopamine, α₁ and α₂ adrenergic receptor antagonists on antinociception of propofol in mice

Zhi-jun Ge
Yin-ming Zeng
Yong-fei Tan
Research01 Feb 2005
Acta Pharmacologica Sinica

Volume: 26, P: 186-191
Microsecond-response perovskite light-emitting diodes for active-matrix displays

An individual-particle passivation strategy that reduces ion migration in perovskite nanocrystal film can be used to make high-refresh-rate active-matrix displays with microsecond response times reduced by three orders of magnitude compared with typical perovskite light-emitting diodes.

Yun Gao
Hongjin Li
Zhizhen Ye
ResearchOpen Access18 Jun 2024
Nature Electronics

Volume: 7, P: 487-496
Tracheoesophageal fistula treated with magnetic compression technique in canines

Yixing Li
Miaomiao Zhang
Xiaopeng Yan
ResearchOpen Access24 Mar 2023
Scientific Reports

Volume: 13, P: 1-7
A novel magnetic compression technique for cystostomy in rabbits

Miaomiao Zhang
Jianqi Mao
Xiaopeng Yan
ResearchOpen Access16 Jul 2022
Scientific Reports

Volume: 12, P: 1-6
Cross sectional pilot study on clinical review generation using large language models

Zining Luo
Yang Qiao
Jiebin Xie
ResearchOpen Access19 Mar 2025
npj Digital Medicine

Volume: 8, P: 1-15
A complete gap-free diploid genome in Saccharum complex and the genomic footprints of evolution in the highly polyploid Saccharum genus

The sugarcane relative, Erianthus rufipilus, is one of the rare diploid species within the Saccharum complex. Its gap-free genome reveals centromere diversification, epigenetics of a palaeo-duplicated chromosome and evolution of Saccharum.

Tianyou Wang
Baiyu Wang
Jisen Zhang
Research30 Mar 2023
Nature Plants

Volume: 9, P: 554-571
Highly anisotropic Fe₃C microflakes constructed by solid-state phase transformation for efficient microwave absorption

Fe₃C microflakes with high magnetic anisotropy are prepared through solid-state phase transformation and electrochemical dealloying. The magnetic anisotropy can be tuned by adjusting the morphology, resulting in optimized ferromagnetic resonance behavior for microwave absorption

Rongzhi Zhao
Tong Gao
Gaowu Qin
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-9
Structure of the mouse TRPC4 ion channel

Members of the transient receptor potential (TRP) ion channels conduct cations into cells upon activation by a variety of signals. Here authors present the cryo-EM structure of TRPC4 in its unliganded (apo) state, which provides molecular insights into TRPC4's ion selectivity and TPR channel evolution.

Jingjing Duan
Jian Li
Jin Zhang
ResearchOpen Access06 Aug 2018
Nature Communications

Volume: 9, P: 1-10
miR-107 regulates tumor progression by targeting NF1 in gastric cancer

Shizhi Wang
Gaoxiang Ma
Meilin Wang
ResearchOpen Access09 Nov 2016
Scientific Reports

Volume: 6, P: 1-8
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease

Liu and colleagues find differential effects of microglial apoE isoforms on brain function and microglial responses. ApoE3 enhances microglial responses, promoting brain function and reducing amyloid deposition and associated neurotoxicity, while the Alzheimer’s disease-associated apoE4 results in lipid droplet accumulation and impaired microglial responses, which are critical for limiting the development of amyloid pathology.

Chia-Chen Liu
Na Wang
Guojun Bu
Research19 Oct 2023
Nature Immunology

Volume: 24, P: 1854-1866
High efficiency and stability of ink-jet printed quantum dot light emitting diodes

Designing efficient and scalable quantum dot LEDs meeting industrial requirements remains a challenge. Here, the authors, by leveraging the liquid phase exchange of d-MX₂ ligands, present printed quantum dot LEDs with external quantum efficiency over 16% and half lifetime of more than 1,721,000 hours.

Chaoyu Xiang
Longjia Wu
Lei Qian
ResearchOpen Access02 Apr 2020
Nature Communications

Volume: 11, P: 1-9
Cas3 of type I-Fa CRISPR-Cas system upregulates bacterial biofilm formation and virulence in Acinetobacter baumannii

Deletion of cas3(type I-Fa) significantly reduced the biofilm formation, virulence and pathogenicity to mice. Mechanism analysis proved that this maybe because cas3 can lead to the down-regulation of biofilm formation related factors and ompA.

Tingting Guo
Jie Yang
Guocai Li
ResearchOpen Access14 May 2025
Communications Biology

Volume: 8, P: 1-10
Blue light-emitting diodes based on colloidal quantum dots with reduced surface-bulk coupling

The surface localized charges in colloidal quantum dots induce a degradation that limits the electroluminescence performance. Here, Chen et al. propose quantum dots with monmonotonically-graded core/shell/shell structures to boost the device’s performance by reducing the surface-bulk coupling.

Xingtong Chen
Xiongfeng Lin
Song Chen
ResearchOpen Access17 Jan 2023
Nature Communications

Volume: 14, P: 1-9
Profiling of RNA N6-Methyladenosine methylation reveals the critical role of m6A in betaine alleviating hepatic steatosis

Yuna Wu
Jingsu Yu
Yixing Li
ResearchOpen Access01 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Monitoring and early warning of ovarian cancer using high-dimensional non-parametric EWMA control chart based on sliding window

Bin Wu
Wen Zhong
Liu Liu
ResearchOpen Access17 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
RIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination

Chen Lu
Hongda Liu
Chunzhao Yu
ResearchOpen Access04 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-16
Large-area patterning of full-color quantum dot arrays beyond 1000 pixels per inch by selective electrophoretic deposition

Colloidal quantum dots are promising for next-generation displays, yet the technology to realise high-resolution and uniform patterning is still scarce. Here, the authors report full-colour QD large area patterning by combining photolithography and selective electrophoretic deposition technique.

Jinyang Zhao
Lixuan Chen
Xiao Wei Sun
ResearchOpen Access29 Jul 2021
Nature Communications

Volume: 12, P: 1-8
Liver knockout of MCU leads to greater dysregulation of lipid metabolism in MAFLD

Qichao Liao
Yurou Zhang
Lei Zhou
ResearchOpen Access15 Nov 2024
Scientific Reports

Volume: 14, P: 1-13
Magnetic anchor technique-assisted thoracoscopic lobectomy in beagles

Yixing Li
Miaomiao Zhang
Xiaopeng Yan
ResearchOpen Access13 Jul 2022
Scientific Reports

Volume: 12, P: 1-7
Research on the anti-ageing mechanism of Prunella vulgaris L.

Ping Li
Xiao Lv
Yadong Yang
ResearchOpen Access31 Jul 2023
Scientific Reports

Volume: 13, P: 1-9
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90

Cachexia affects many cancer patients causing weight loss and increasing mortality. Here, the authors identify extracellular Hsp70 and Hsp90, either in soluble form or secreted as part of exosomes from tumor cells, to be responsible for tumor induction of cachexia.

Guohua Zhang
Zhelong Liu
Yi-Ping Li
ResearchOpen Access19 Sept 2017
Nature Communications

Volume: 8, P: 1-16
Translatomics reveals the role of dietary calcium addition in regulating muscle fat deposition in pigs

Jingsu Yu
Xiangling Li
Yixing Li
ResearchOpen Access29 May 2024
Scientific Reports

Volume: 14, P: 1-17
MiR-183-5p inhibits lung squamous cell carcinoma survival through disrupting hypoxia adaptation mediated by HIF-1α/NDUFA4L2 axis

Peng Han
Boxiang Zhang
Yiqian Liang
Research17 Aug 2024
Oncogene

Volume: 43, P: 2821-2834
Association of increased Treg and Th17 with pathogenesis of moyamoya disease

Leihua Weng
Xiang Cao
Yun Xu
ResearchOpen Access08 Jun 2017
Scientific Reports

Volume: 7, P: 1-8
Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways

Guohua Zhang
Zhelong Liu
Yi-Ping Li
ResearchOpen Access23 May 2017
Scientific Reports

Volume: 7, P: 1-8
Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls

The authors perform a genome-wide association study of adolescent idiopathic scoliosis patients of Han Chinese descent, and identify 3 new loci for disease susceptibility.

Zezhang Zhu
Nelson Leung-Sang Tang
Jack Chun-Yiu Cheng
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-6
Multiple electron transporting layers and their excellent properties based on organic solar cell

Ziyan Yang
Ting Zhang
Song Chen
ResearchOpen Access29 Aug 2017
Scientific Reports

Volume: 7, P: 1-9
The schizophrenia-associated missense variant rs13107325 regulates dendritic spine density

Shiwu Li
Changguo Ma
Xiong-Jian Luo
ResearchOpen Access02 Sept 2022
Translational Psychiatry

Volume: 12, P: 1-12

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