Barcodes that composed of multiple colloidal crystal or magnetic-tagged ETPTA cores and PEG hydrogel shells were developed by using microfluidics. As the cores are with distinct reflection peaks, the barcodes allow for substantial number of coding levels for multiplexing. The hydrogel shells surrounding the barcodes enable the creation of three-dimensional scaffolds for immobilizing probes. Moreover, the presence of magnetism in the barcodes confer them controllable movement under magnetic fields, which could significantly increase the sensitivity and simplify the processing of the bioassays.
- Yuanjin Zhao
- Zhuoying Xie
- Zhongze Gu
