Extended Data Fig. 6: Crossover-adjusted analysis of overall survival by IPCW model. | Nature Medicine

Extended Data Fig. 6: Crossover-adjusted analysis of overall survival by IPCW model.

From: Surgery versus no surgery in platinum-sensitive relapsed ovarian cancer: final overall survival analysis of the SOC-1 randomized phase 3 trial

Extended Data Fig. 6

a, IPCW curves. P values were two-sided with no adjustment of multiplicity, P = 0.019. HRs and the corresponding 95% two-sided CIs were estimated using a Cox proportional hazards model. b, Covariates selection for inverse-probability-of-censoring weights model. Numbers of patients at risk are not included for the IPCW curve due to the lack of a clear clinical interpretation of the number of patients at risk associated with the weighted methodology. * Selected by a model or by clinical consideration; iMODEL score was not selected due to the collinearity with CA125 at 1st relapse and platinum-free interval before 1st relapse. BMI = Body Mass Index. IPCW = inverse probability censoring weighting. CA125 = Cancer antigen 125. ECOG = Eastern Cooperative Oncology Group. FIGO = International Federation of Gynecology and Obstetrics. iMODEL = the international model.

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