Fig. 6: Clinical relevance of RAGA/CD47 axis.
From: RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation
a Overall survival analysis of 84 lung adenocarcinoma patients with low and high CD47 protein expression. P = 0.0071. b Overall survival analysis of 84 lung adenocarcinoma patients with low and high RAGA protein expression. P = 0.0101. c Overall survival analysis of 84 lung adenocarcinoma patients with RAGAhighCD47high, RAGAhighCD47low, RAGAlowCD47high, and RAGAlowCD47low protein expression. P = 0.0127. d Overall survival analysis of lung adenocarcinoma patients with RAGAhighCD47low and RAGAlowCD47high protein expression. P = 0.0017. e Representative immunohistochemistry staining of RAGAhighCD47low and RAGAlowCD47high patient samples. f Pearson correlation coefficient analysis of RAGA and CD47 expression in 84 lung adenocarcinoma patients. Pearson r = −0.2929. P = 0.0069. P < 0.05 is considered statistical significance.
