Fig. 6: 16p11.2 DEL mice show decreased PPI. | Communications Biology

Fig. 6: 16p11.2 DEL mice show decreased PPI.

From: 16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability

Fig. 6

a The startle reflex is unaltered but b PPI is significantly reduced in 16p11.2 DEL mice. a Data shown as mean ± s.e.m. b Box plots show median and interquartile range with “Tukey” whiskers. WT = wild-type mice, 16p11.2 DEL = 16p11.2 deletion mice. Data are pooled for sex as no significant sex x genotype interaction was found (ANOVA). PPI was assessed at 3 different prepulse sound intensities –4, 8 and 16 dB above background. n = 16 (8 male) mice/genotype. **P < 0.01, ANOVA main effect of genotype.

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