Fig. 7: METTL14 or miR-6858 suppression blocks LPS- or activated CD4+ T cells-triggered cell apoptosis. | Communications Biology

Fig. 7: METTL14 or miR-6858 suppression blocks LPS- or activated CD4+ T cells-triggered cell apoptosis.

From: METTL14-upregulated miR-6858 triggers cell apoptosis in keratinocytes of oral lichen planus through decreasing GSDMC

Fig. 7

Caspase 3 activity and protein expression in control- or shMETTL14-lentivirus-infected HOKs with 12-hour LPS (a) or activated CD4+ T cells (b) treatment. Caspase 3 activity and protein expression in 200 nM control- or miR-6858 inhibitors-transfected HOKs with 12-hour LPS (c) or activated CD4+ T cells (d) treatment. n = 3. **P < 0.01, ***P < 0.001 vs corresponding control group; ##P < 0.01, ###P < 0.001 vs corresponding LPS or CD4 group. Data were expressed as means ± standard deviation. All experiments were carried out at least 3 times. One-way ANOVA (a, b, c and d) was used for statistical analysis.

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