Fig. 3: RNA-sequencing showed that CTSB knockout in renal proximal tubular epithelial cells decreased glycolysis.
From: Cathepsin B-dependent glycolysis contributes to reduced renal uric acid excretion in hyperuricemia
a DEG after CTSB knockout in the renal proximal tubular epithelial cells of HUA mice. b Volcano plot and c heatmap of the top DEGs in renal proximal tubular epithelial cells in HUA mice after CTSB knockout. d GO analysis of downregulated and e upregulated pathways after CTSB knockout in the renal proximal tubular epithelial cells of HUA mice. f KEGG analysis of downregulated and g upregulated pathways in renal proximal tubular epithelial cells after CTSB knockout in HUA mice. n = 4.
