Fig. 4: Glycolysis was increased in the kidneys of HUA mice.
From: Cathepsin B-dependent glycolysis contributes to reduced renal uric acid excretion in hyperuricemia
a Western blot of HK2 and PKM2 in kidneys of HUA mice. Statistical analysis of b HK2 and c PKM2 protein expression. Immunofluorescence staining of d HK2 and e PKM2 in the kidneys of HUA mice. f Western blot of HK2 and PKM2 in the kidneys of uricase-knockout mice. Statistical analysis of g HK2 and h PKM2 protein expression. Immunofluorescence staining of i HK2 and j PKM2 in the kidneys of uricase knockout mice. Bars = 25 μm. n ≥ 3. *P < 0.05, **P < 0.01.
