Fig. 6: CAG induce insulin resistance though the activation of dectin-1 pathway. | Communications Biology

Fig. 6: CAG induce insulin resistance though the activation of dectin-1 pathway.

From: Abnormal proliferation of gut mycobiota contributes to the aggravation of Type 2 diabetes

Fig. 6

a, b The colon dectin-1 level of the C. albicans-treated or CAG-treated mice (n = 3 mice per group), c, d The expression of irf-5, syk and arg-1 in colon, e, f The expression of ZO-1 and occludin in colon, g, h The serum levels of IL-1β, IL-10, IL-6, and TNF-α. Data are presented as the mean ± standard error of the mean (SEM); n = 9 mice per group. Statistical analysis was done using one-way ANOVA followed by the Tukey post hoc test. *P < 0.05; **P < 0.01 and ***P < 0.001 vs HFD-WT group.

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