Fig. 5: The extended TimeTalk workflow for deciphering cell-cell communication in blastoid. | Communications Biology

Fig. 5: The extended TimeTalk workflow for deciphering cell-cell communication in blastoid.

From: TimeTalk uses single-cell RNA-seq datasets to decipher cell-cell communication during early embryo development

Fig. 5

a The updated version of TimeTalk. b The re-analysis of the EPS-blastoid dataset. Trajectories were plotted in the UMAP embeddings. The color bar on the right side indicates the pseudotime. c The percentage of different cell types in naturally developed blastocysts and EPS-blastoids. d The Venn diagram shows the overlap of LR pairs in blastocyst and blastoid. There, EPI lineage as a sender cell and PE lineage as a receiver cell. e The KEGG analysis of genes consists of LR pairs mediated EPI-PE communication.

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