Fig. 4: Correlation of DUF2345 domains and downstream toxins.

A Sankey diagram showing the relationship between bacterial phylum/class, family, the corresponding DUF2345 clusters and the downstream toxin ___domain families (from left to right). Only DUF2345-encoding loci with adjacent known toxin domains were included. Loci from genomes without necessary taxa information were excluded. The number of sequences involved in each node is given after the node name. The red arrows on the right indicate some toxins which were linked to more than one DUF2345 clusters.