Fig. 3: Integrated analysis of scRNA seq and ATAC-seq at bulk level. | Communications Biology

Fig. 3: Integrated analysis of scRNA seq and ATAC-seq at bulk level.

From: Single-cell immune profiling and validation of PBMCs in the onset of and recovery from herpes zoster

Fig. 3

a Strategy to integrated analysis DEGs and DARs at bulk level. b Gene-OCR pairs determined by log2(fold change) of scRNA-seq and ATAC-seq at the bulk level. c The top 8 motifs motif analysis of the up-regulated Peaks and the predicted motif-related key transcription factors are shown. d Genome browser showing bulk-level ATAC-seq results for OCRs corresponding to key genes enriched in scRNA-seq analysis between HA and HP are displayed. e GO analysis of biological processes related to more open chromatin regions and less open chromatin regions. KEGG analysis of biological processes related to f more open chromatin regions and g less open chromatin regions.

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