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Conventional electrochemical evaluations severely decelerate the iteration of long-life batteries. Here, the authors unpuzzle the myth of coulombic loss contrary to prevailing understanding. Physical-correlated coulombic-capacity relation is pivotal for rapid battery screening and prognostics.

A cost-effective all-in-one halide cathode material with high energy density and exceptional cycling stability can be used to achieve energy-dense, durable cathodes for the next generation of all-solid-state batteries.

High-energy aqueous metal batteries are promising candidates for the next-generation energy storage systems yet face detrimental parasitic reactions. Here, authors develop a durable cadmium-metal battery employing a fast-kinetics dual-structure-breaking electrolyte.

Polymer electrolytes are promising but are limited by narrow electrochemical window. Here, authors develop a family of in situ polymerized gel electrolytes with long term stability up to 5.0 V and develop a non-destructive life extension strategy through freezing the cells.

A miniaturized and low-power-consumption system is designed to allow the accurate sensing and wireless transmission of internal temperature and strain signals inside lithium-ion batteries with negligible influence on their performance, improving their safety.

Electrolyte interactions critically govern battery performance yet lack precise design principles. The authors introduce interaction motif descriptors to design an electrolyte enabling 99.7% Li-metal Coulombic efficiency for 4.5 V batteries.

LepR⁺ cells senescence is a driver of aging-induced bone marrow homeostasis collapse. Here, Li et al. report a LepR⁺ cell-targeting nitric oxide (NO) nanopump for rejuvenation of senescent LepR⁺ cells via activation of glycolysis signaling to reestablish homeostasis of the aged bone marrow.

The realization of high-performance flexible perovskite/crystalline-silicon tandem solar cells requires efficient photocarrier transport and mitigation of residual stress. Here, authors reveal the critical role of perovskite phase homogeneity, achieving flexible devices with efficiency of 29.88%.

Ultra-low-temperature lithium metal batteries struggle with slow ion transport and dendrite growth. Here, authors develop a multifunctional electrolyte additive (PQA-NO₃) that forms a protective SEI layer and modifies ion interactions, enabling stable operation at extreme cold condition of −85 °C.

Complex traits present challenges for gene mapping and molecular characterization. Here, the authors develop a 16-generation intercross line of chickens to explore the genetic architecture of complex traits in chicken.

Exfoliation of g-C₃N₄ breaks the molecular chains, causing sluggish carrier kinetics and moderate degradation activity. Here, authors address these issues by developing an ultrathin porous g-C₃N₄ with intact molecular chains via shear repair strategy, enhancing the activity of PMS-assisted water purification.

Ultrafast electron sources are essential for time-resolved electron microscopy techniques, but they usually suffer from limited stability and short lifetimes. Here, the authors report the fabrication of ultrafast hot-electron sources consisting of graphene films integrated on a single-mode optical fibre, showing enhanced stability and longevity.

A three-dimensional metal stamp can be used to selectively exfoliate two-dimensional materials, allowing the remaining material to be patterned into two-dimensional arrays without leaving chemical or polymer residues.

Epstein-Barr virus is associated with increased cancer risk. Here, the authors analysed two population-based prospective cohorts in Southern China to examine the association between increased seropositivity and the risk of multiple cancer types.

Combining antibody drug conjugates (ADCs) and tyrosine kinase inhibitors (TKIs) targeting HER2 has been shown to improve efficacy in patients with advanced HER2+ breast cancer. Here, the authors report a randomised phase 2b trial comparing neoadjuvant ARX788 (HER2 ADC) plus pyrotinib (HER1, HER2 and HER4 TKI) against neoadjuvant standard of care (docetaxel, carboplatin, trastuzumab, and pertuzumab) for the treatment of HER2+ breast cancer.

The influence of Li occupancy on electro-chemomechanical stability in Co-free Ni-rich layered oxides for Li-ion batteries has been overlooked. Here, authors investigate different Li structural units in the oxide lattice and show that tuning the Li occupancy improves battery cycling stability.

White-light emission from materials and devices usually occurs omni-directional through space. Here, the authors show that sintering carbon dots with TiO₂ forms a microlens-shape surface that enables directional emission with 1/60 solid angle.

Reactivity between Na₃Zr₂Si₂PO₁₂ solid electrolyte and sodium metal limits battery performance. Here, the authors strengthen the P-O covalency by Na₂SiF₆ doping and introduce a SnF₂ coating to reduce parasitic reactions and create a sodiophilic interface, enabling 1200 cycles at 5 C of a solid-state battery with Na₃V₂(PO₄)₃.

Rehmannia chingii is a traditional Chinese medicinal plant that can produce iridoid glycoside. Here, the authors report its genome assembly and the elucidation of the iridoid biosynthetic pathway.

The heterogeneity of HSPCs in response to IR stress remains poorly characterized. Here, the authors provide insights into the molecular intricacies of IR-induced BM injury and reveal the roles of BMP4-BMPR2 signaling in radiation resistance of HSCs.

Whether multimorbidity accelerates brain Aβ deposition in humans remains largely unknown. Here, the authors demonstrate that higher self-reported multimorbidity burden predicts increased brain Aβ accumulation rates in the ADNI cohort.

Zhang et al. report the incorporation of copper halide perovskite nanocrystals into glass fibre arrays for high-resolution remote scintillation over 5 m without crosstalk. Real-time and 3D X-ray imaging are demonstrated employing 1600 densely packed fibres with a single pixel diameter of about 10.4 µm.

The authors demonstrate resonant excitation of phonon-polaritons based on THz-driven ZnO single crystals. This clarifies the generation mechanism of phonon-polaritons, enabling their observation for various nonlinear regimes.

In ABA trilayer graphene, a temperature gradient generates a transverse voltage that scales quadratically with the gradient and reaches an effective Nernst coefficient of 300 µV K⁻¹ near the charge neutrality point.

Surface high-valent iron-oxo species (≡Fe⁴⁺=O) are effective and environmentally friendly reagents for oxygen atom transfer. Here, the authors create a planar, asymmetric ≡Fe⁴⁺=O with a Fe–Cl₁S₃ structure using pyrite and chlorite, which enhances electron delocalization and weakens the Fe=O bond to improve reaction efficiency.

Current lithium-ion battery recycling extracts valuable metals while discarding much of the battery’s leftover value. An emerging strategy called direct battery regeneration upends this model, restoring the battery’s performance without taking it apart — presenting a more efficient, sustainable option for end-of-life batteries.

The zoonotic parasite Toxoplasma has complex developmental programs to accommodate different lifestyles that are important for parasite transmission and pathogenesis. Here, the authors discover a novel chromatin remodeling complex containing SNF2L in Toxoplasma and report its crucial roles in regulating the parasite’s developmental programs.

DNA Damage Regulated Autophagy Modulator 1 (DRAM1) plays pivotal roles in autophagy regulation. Here, the authors show that DRAM1 stabilizes lysosomal VAMP8, thereby promoting autolysosome maturation. Furthermore, they establish that DRAM1–VAMP8 axis enhances autophagic flux and facilitates hepatocellular carcinoma extravasation, as validated in both zebrafish xenograft and mouse metastatic models.

An RNA codon-expansion strategy enables incorporation of non-canonical amino acids into proteins of interest orthogonally to existing methods by inserting pseudouridine codons into specific mRNA transcripts and using an engineered decoder tRNA.

This study presents an approach that directly converts commercial polycrystalline Li into various monocrystalline Li metal anodes with single facets via a recrystallization technique. Using monocrystalline Li(110), the critical current density can be raised by an order of magnitude in solid-state batteries.

A soft mesh microelectrode array can seamlessly integrate in developing brains, enabling long-term, stable mapping of how single-neuron activity and population dynamics emerge and evolve during brain development.

The specific capacity of an important commercial cathode material, lithium iron phosphate, is much lower than its theoretical value. Hu et al. report that incorporation of electrochemically exfoliated graphene layers in a carbon coating improves capacity beyond that predicted by theory.

Proton transfer plays a key role in nature, yet its ultrafast dynamics remain elusive. Here the authors use coincidence spectroscopy and theoretical simulations to show that radiolytic doubly-ionized pyrrole triggers proton transfer to water within 60 fs.

This study uses deep learning and gaze-tracking to track pathologists' work and learn how they review tissue images. This “learned expertise” was applied to guide artificial intelligence models, such as weakly supervised learning and reinforcement learning, to achieve accurate diagnosis of Whole Slide Images.

A F-containing additive with efficient LiF contribution is urgent for Li metal batteries. The authors report a hexafluoroglutaric anhydride additive with a 91% conversion, enabling the Li metal anode with a LiF-rich interphase in regular electrolyte.

ELD1, a CCHC-type zinc finger protein, is found to modulate alternative splicing of the core oscillator gene OsCCA1 and thereby regulate photoperiodic flowering in rice. This reveals additional links between light signaling and the circadian clock.

A new asymmetric non-fullerene acceptor, P2EH-1V, is designed and synthesized for constructing devices demonstrating record-high efficiencies of 26.7% (certified at 26.4%) over an aperture area greater than 1 cm² in perovskite–organic tandem solar cells.

Cation solvation in batteries is well understood in bulk solutions but less so at electrode/electrolyte interfaces. This study reveals how external and intramolecular fields affect Li-ion solvation, proposing a dielectric protocol to enhance cation–anion coordination and improve performance in Li-metal pouch cells.

There is growing interest in designing electrolytes to enable Li-metal batteries. Here the authors show that asymmetric solvents improve lithium redox kinetics and achieve long cycle life in anode-free cells under electric vertical take-off and landing conditions, demonstrating potential for future high-power applications.

Lithium–sulfur batteries are a promising electrochemical energy storage technology; however, they are limited by the dissolution of polysulfide intermediates. Now, it has been shown that sparingly solvating electrolytes containing a phase mediator can avoid polysulfide dissolution and accelerate surface-localized solution-phase sulfur reaction to improve battery performances.

Tao et al. study the role of TRMT6 in colorectal cancer, where it is upregulated and show that TRMT6 supports histone biosynthesis by stabilizing tRNA-Lys-TTT-1-1. Targeting TRMT6 reduced histone mRNA translation in a codon-biased manner.

A facile light-triggered doping strategy involving a series of inactive photoactivable dopants is described that facilitates tunable regionally controlled n-doping of organic semiconductors, resulting in stable patterning of the doping profile at record high resolutions.

The high-voltage oxygen redox activity of Li-rich layered oxides enables additional capacity beyond conventional transition metal redox contributions. Here, authors investigate the correlation between oxygen redox activity and superstructure units. They prove that an excess of LiNiMn5 hinders the extraction/insertion of lithium ions.

Two genetically linked TdNLR genes from wild emmer wheat are both required for YrTD121-mediated stripe rust resistance. The TdNLR1 and TdNLR2 pair lacks an integrated ___domain, representing an uncommon architecture for paired NLRs in plants.

The instability of lithium metal hinders the commercialization of lithium-metal batteries. This Review explores polymer coatings as a promising solution, summarizing key design principles, effective coatings and future interface strategies.

Kidney stone disease is increasing worldwide. Cao et al. perform a cross-ancestry GWAS meta-analysis of the condition, identifying risk loci and potential causal variants, and construct a cross-population polygenic risk score.

Detecting small molecules is pivotal across many fields. Here, authors leverage a split crRNA mode to construct spatially blocked split CRISPR-Cas12a system. This approach establishes a low-background, highly sensitive platform for small molecule detection.