Search

Detailed mechanistic study is challenging but meanwhile benefits rational design of electrocatalysts. Here the authors report bimetallic phosphide for bifunctional hydrazine oxidation and hydrogen evolution reaction and reveal hydrazine oxidation pathways as well as the recovery of metal phosphide active site by N₂H₄ molecules.

Wafer-scale two-dimensional transition metal selenides, with high structural quality and environmental stability, can be obtained by two-step vapour deposition in oxygen-free conditions. The grown films maintain robust superconductivity even after harsh treatments.

Low-loss superconducting aluminium cables and on-chip impedance transformers can be used to link qubit modules and create superconducting quantum computing networks with high-fidelity intermodule state transfer.

Limited tumor penetration and low cellular uptake of current nanocarriers reduce the efficacy of anticancer drugs against TNBC. Here the authors develop biomimetic head/hollow tail nanorobots and show their efficacy at remodeling the dense tumor stroma in TNBC.

C₂H₄ is one of the most important chemical raw materials. Here, the authors report that tuning of pore structure shifts the multi-component gas separation function, enabling one-step production of high-purity C₂H₄ in the quaternary mixture.

Newly evolved Xanthomonas citri pv. malvacearum isolates triggers recent bacterial blight outbreaks in cotton. Here, the authors show that a recently evolved TALE, Tal7b, activates host susceptibility genes GhSWEET14a and GhSWEET14b rather than GhSWEET10 to confer pathogenicity in these new isolates.

Wu et al. elucidate the molecular basis for SCOOPs perception by the MIK2–BAK1 immune complex and demonstrate an unexpectedly pivotal role of N-glycans in plant receptor–coreceptor interactions and signalling activation, shaping immune responses.

Separating ethylene from ethane is highly challenging as they have very similar physical properties. Here, a metal–organic framework is reported that, owing to its pore size and rigidity, adsorbs ethylene but almost completely excludes ethane under ambient conditions.

Two-dimensional materials show great potential for membrane technologies, but their disordered channels hinder their molecular sieving performance. Here, Wang, Gogotsi and colleagues design a MXene membrane with ordered nanochannels that exhibits an excellent H₂/CO₂ gas separation performance.

Porous materials are promising candidates for the cost- and energy-efficient separation of ethylene and ethane from gas mixtures: an important but challenging industrial process. Now, a hydrogen-bonded organic framework has been reported that is stable under harsh conditions and can take up ethylene at practical temperatures—with very high selectivity over ethane—through a gating mechanism.

The large-scale fabrication of twisted van der Waals heterostructures remains challenging due to the formation of defects and contaminations during the transfer process. Here, the authors report a transfer method to fabricate graphene-based van der Waals superlattices at the wafer scale, showing controllable twist angles and robust quantum Hall effect.

Carbon materials are widely used in electrochemical technologies. However, their intrinsic conductivity deteriorates over time. Here the authors build a highway-mediated nanoarchitecture of ordered pseudographitic nanodomains to promote charge transfer for electrochemical ion capture.

Genetic variation from coexisting species influences interspecific interactions in a community. Here, the authors develop a framework for identifying quantitative trait loci (QTLs) underlying community dynamics and validate the tool using data from co-culturing of two bacterial species.

The mechanism of the charge density wave in kagome metals is not fully understood. Here, the authors report the observation of unusual large-frequency collective lattice excitations, or amplitude modes, in CsV₃Sb₅ in the absence of phonon mode softening, evidencing the strong electron-phonon coupling regime.

Domain wall formation and propagation using a small electric voltage are demonstrated in ferro-rotational 1T-TaS₂, although the ferroic order does not couple with electromagnetic fields, providing an opportunity for the manipulation and application of ferro-rotational order.

A growth process in which protons decouple graphene from the underlying substrate greatly reduces the number of wrinkles that usually degrade large graphene films grown by chemical vapour deposition.

Low activity of the oxygen reduction reaction (ORR) in polymer electrolyte membrane fuel cells is a barrier for commercial applications. Here the authors report a nickel boride membrane-coated Pt-Ni catalyst, achieving 27-fold enhancement in mass activity for ORR relative to commercial Pt/C.

The voltage-gated sodium channel Na_v1.7 has a dual role in osteoarthritis—in chondrocytes, it promotes joint damage, and in dorsal root ganglia neurons, it increases pain transmission.

Stacks of van der Waals superconductor heterostructures comprising many layers and several blocks of two-dimensional materials have been grown in a highly controllable manner at a wafer scale using a high-to-low temperature strategy.

Bin Zhou and colleagues use genetic labeling in mice to show that endocardial cells of the sinus venosus substantially contribute to the liver vasculature, which thus shares a common developmental origin with coronary arteries. Inhibition of endocardial angiogenesis leads to reduced endocardial contribution to the liver vasculature and to defects in liver organogenesis.

The film uniformity is essential to the fixed pattern noise (FPN) and resolution of X-ray detectors. Here the authors demonstrate the rheological engineering of the perovskite suspension to achieve low FPN of 1.39% and high resolution of 0.51 lp/pix.

To run algorithms on a computer they are broken down into logical operations that are implemented in hardware. A quantum logical AND gate has now been demonstrated, which could substantially improve the efficiency of near-term quantum computers.

Chemical vapour deposition is one of the most promising strategies to grow high-quality graphene sheets on a large scale. It is now shown that this deposition technique can be extended to grow three-dimensional graphene networks with high conductivity and flexibility—both promising features for flexible electronics.

A plant endogenous peptide-receptor signaling pathway termed SCREW–NUT is described; it counteracts microbe-associated molecular pattern (MAMP)- and abscisic acid-induced stomatal closure to regulate the reopening of stomata after biotic and abiotic stresses.

Peptide signals generated during plant microbe interactions can trigger immune responses in plants. Here the authors show that SCOOP12, a member of a family of peptides present in Brassicaceae plants, and SCOOP12-like motifs in Fusarium fungi, can trigger immune responses following perception by the MIK2 receptor kinase.

Bin Han and colleagues report the draft genome sequence of the grass carp Ctenopharyngodon idellus, a major commercially farmed species of freshwater fish. Analyses of the grass carp genome identify lineage-specific duplications that may have contributed to the adaptation of this species to a vegetarian diet.

Plants have two mechanisms to respond to infection; pattern-triggered immunity detects conserved microbial compounds, whereas effector-triggered immunity recognizes proteins secreted by pathogens. In this study, Cheng et al. report that temperature determines which of these immune systems is preferentially induced.

Apelin expression is robust in embryonic but not in adult endothelial cells (ECs), where it can be reactivated by hypoxia. Liu et al. show that apelin-driven expression of Cre recombinase in mice can be used for labelling of, or gene ablation in, sprouting but not quiescent ECs in pathologies characterized by hypoxia.

The detection of microorganism-associated ligands by plant cells activates a signalling cascade in which the kinase BIK1 is monoubiquinated, released from the FLS2–BAK1 complex, and internalized by endocytosis.

MAPK signaling suppresses autoimmunity mediated by the SUMM2 receptor in Arabidopsis. Here Huang et al. show that a trimeric complex consisting of the GPI anchored protein LLG1, and the two receptor-like proteins LET1 and LET2, promotes activation of SUMM2 according to MAPK signaling status.

Plants deploy numerous receptor-like kinases (RLKs) to respond to pathogens. Here the authors show that NIK1, an RLK that positively regulates antiviral immunity, negatively regulates the response to bacteria by modulating FLS2/BAK1 complex formation, suggesting crosstalk between bacterial and viral immunity.

Fate-mapping and clonal analysis show that bronchioalveolar stem cells (BASCs) become activated and respond distinctly to different lung injuries and differentiate into multiple cell types. Single-cell RNA-seq analysis identifies new BASC markers.

Observational analyses from the China Kadoorie Biobank found that alcohol consumption was associated with higher risks of 61 diseases in Chinese men, with most of these associations confirmed by genetic analyses.

Hepatocytes are highly specialized cells and their fate is determined by their position in the liver as either periportal or perivenous hepatocytes. Here, Pu et al. show through genetic lineage tracing for Mfsd2 that periportal hepatocytes proliferate and reprogram into pericentral hepatocytes during liver regeneration and injury.

Transcription activator-like effectors contribute to virulence of theXanthomonas strain responsible for bacterial blight in cotton. Here Cox et al. show that the XanthomonasAvrb6 effector induces expression of the cotton SWEET10 sugar transporter and that this induction promotes disease.

Mei (Prunus mume) is a woody tree that produces ornamental blossoms which symbolize spring in East Asia. Here, Zhang et al. resequence wild and domesticated mei to reveal considerable admixture and introgression from other Prunus species and identify loci associated with floral traits.

Studying the genetic progression of many cancers is difficult as longitudinal samples are rarely available. Here, the authors analyse a patient with chronic lymphocytic leukaemia over a 29 year period and track the clonal evolution of the patient’s disease and response to therapy.

Fetal trabecular muscles in the heart undergo a poorly described morphogenetic process that results into a solidified compact myocardium after birth. Tian et al. show that cardiomyocytes in the fetal compact layer also contribute to this process, forming a hybrid myocardial zone that is composed of cells derived from both trabecular and compact layers.

Control of cell death is crucial for plant life. A comprehensive screen for suppressors of BAK1/SERK4-mediated cell death identified a component of protein glycosylation pathways and ERQC, and its cysteine-rich receptor-like kinase (CRK) targets.