Nature Search

A map of blood regulatory variation in South Africans enables GWAS interpretation

This study maps regulatory variation in blood using whole-genome and transcriptome data from 614 South Africans, providing a resource to aid the interpretation of genome-wide association studies in African populations.

Stephane E. Castel
Furahini D. Tluway
Michèle Ramsay
ResearchOpen Access11 Jun 2025
Nature Genetics

P: 1-10
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

Estimates from the Global Dietary Database indicated that 2.2 million new type 2 diabetes and 1.2 million new cardiovascular disease cases were attributable to sugar-sweetened beverages worldwide in 2020, with the highest burdens in sub-Saharan Africa, Latin America and the Caribbean.

Laura Lara-Castor
Meghan O’Hearn
Rubina Hakeem
ResearchOpen Access06 Jan 2025
Nature Medicine

Volume: 31, P: 552-564
Sugar-sweetened beverage intakes among adults between 1990 and 2018 in 185 countries

Recent estimates of sugar-sweetened beverages (SSBs) intake are generally unavailable. Here the authors show a global SSBs intake of 2.7 servings/week in 2018 in adults (range: 0.7 South Asia, 7.8 Latin America/Caribbean); intakes were higher among males, younger, more educated, and urban adults.

Laura Lara-Castor
Renata Micha
Rubina Hakeem
ResearchOpen Access03 Oct 2023
Nature Communications

Volume: 14, P: 1-19
Children’s and adolescents’ rising animal-source food intakes in 1990–2018 were impacted by age, region, parental education and urbanicity

An analysis based on data from the Global Dietary Database shows mean animal-sourced food intakes among children and adolescents increased modestly from 1990 to two portions per day in 2018, but remain low in sub-Saharan Africa, India and Bangladesh.

Victoria Miller
Patrick Webb
Rubina Hakeem
ResearchOpen Access20 Apr 2023
Nature Food

Volume: 4, P: 305-319
Global dietary quality in 185 countries from 1990 to 2018 show wide differences by nation, age, education, and urbanicity

Dietary quality is reported at the global, regional and national level across 185 countries. Though diet quality increased modestly since 1990 at the global level, in South Asia and Sub-Saharan Africa it did not improve. In some regions, children’s dietary quality is lower than that of adults.

Victoria Miller
Patrick Webb
Rubina Hakeem
ResearchOpen Access19 Sept 2022
Nature Food

Volume: 3, P: 694-702
Coding and regulatory variants are associated with serum protein levels and disease

Finding the genetic basis of protein expression can elucidate the genetic mechanisms of disease. Here, the authors link low-frequency and common DNA sequence variants to thousands of serum proteins, finding genetic overlap between circulating proteins and a wide range of common diseases.

Valur Emilsson
Valborg Gudmundsdottir
Vilmundur Gudnason
ResearchOpen Access25 Jan 2022
Nature Communications

Volume: 13, P: 1-11
An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci

Open Targets Genetics is a community resource that provides systematic fine mapping at human GWAS loci, enabling users to prioritize genes at disease-associated regions and assess their potential as drug targets.

Edward Mountjoy
Ellen M. Schmidt
Maya Ghoussaini
Research28 Oct 2021
Nature Genetics

Volume: 53, P: 1527-1533
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Incident type 2 diabetes attributable to suboptimal diet in 184 countries

Modeling analysis from the Global Dietary Database estimated that 70% of new global cases of type 2 diabetes are attributable to suboptimal intake of 11 dietary factors, with substantial differences in dietary risks across world regions and nations.

Meghan O’Hearn
Laura Lara-Castor
Rubina Hakeem
ResearchOpen Access17 Apr 2023
Nature Medicine

Volume: 29, P: 982-995
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Surface profile analysis of laminated transfemoral prosthetic socket fabricated with different ratios of epoxy resin and acrylic resin

Nik Abdul Muiz Nik Zainuddin
Nasrul Anuar Abd Razak
Noor Azuan Abu Osman
ResearchOpen Access15 Feb 2023
Scientific Reports

Volume: 13, P: 1-8
Enhancing shielding efficiency of ordinary and barite concrete in radiation shielding utilizations

Nasuha Ahmad
Mohd Idzat Idris
Rafidah Zainon
ResearchOpen Access29 Oct 2024
Scientific Reports

Volume: 14, P: 1-22
Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs

David Ochoa
Mohd Karim
Ian Dunham
News08 Jul 2022
Nature Reviews Drug Discovery

Volume: 21, P: 551
An automated privacy-preserving self-supervised classification of COVID-19 from lung CT scan images minimizing the requirements of large data annotation

Sadia Sultana Chowa
Md Rahad Islam Bhuiyan
Sami Azam
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-20
Author Correction: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

Laura Lara-Castor
Meghan O’Hearn
Rubina Hakeem
Amendments and CorrectionsOpen Access28 Jan 2025
Nature Medicine

Volume: 31, P: 696
Triglyceride to HDL-C Ratio is Associated with Insulin Resistance in Overweight and Obese Children

Nur Ahmad Kamil Zati Iwani
Muhammad Yazid Jalaludin
Wan Mohamud Wan Nazaimoon
ResearchOpen Access06 Jan 2017
Scientific Reports

Volume: 7, P: 1-7
Multilayer patch functionalized microfibrillated cellulosic paper sensor for sweat glucose monitoring

Zoheb Karim
Mohd Jahir Khan
Zishan Husain Khan
ResearchOpen Access08 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
Employing deep learning and transfer learning for accurate brain tumor detection

Sandeep Kumar Mathivanan
Sridevi Sonaimuthu
Mohd Asif Shah
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
CoMOGrad and PHOG: From Computer Vision to Fast and Accurate Protein Tertiary Structure Retrieval

Rezaul Karim
Mohd. Momin Al Aziz
Salman Rakin
ResearchOpen Access21 Aug 2015
Scientific Reports

Volume: 5, P: 1-11
Bootstrapping random forest and CHAID for prediction of white spot disease among shrimp farmers

Michael Onyema Edeh
Surjeet Dalal
Ademola Olusola Adesina
ResearchOpen Access03 Dec 2022
Scientific Reports

Volume: 12, P: 1-12
Validation of a roughness parameters for defining surface roughness of prosthetic polyethylene Pe-Lite liner

Nur Afiqah Hamzah
Nasrul Anuar Abd Razak
Siti Zuliana Salleh
ResearchOpen Access16 Feb 2022
Scientific Reports

Volume: 12, P: 1-9
Diaporthe species causing stem gray blight of red-fleshed dragon fruit (Hylocereus polyrhizus) in Malaysia

Abd Rahim Huda-Shakirah
Yee Jia Kee
Masratul Hawa Mohd
ResearchOpen Access16 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Homalomena pineodora essential oil nanoparticle inhibits diabetic wound pathogens

Nur Amiera Syuhada Rozman
Tong Woei Yenn
Kok Chang Lee
ResearchOpen Access24 Feb 2020
Scientific Reports

Volume: 10, P: 1-11
Processing-Structure-Property Correlation Understanding of Microfibrillated Cellulose Based Dimensional Structures for Ferric Ions Removal

Zoheb Karim
Anna Svedberg
Mohd Jahir Khan
ResearchOpen Access16 Jul 2019
Scientific Reports

Volume: 9, P: 1-12
Author Correction: Global dietary quality in 185 countries from 1990 to 2018 show wide differences by nation, age, education, and urbanicity

Victoria Miller
Patrick Webb
Rubina Hakeem
Amendments and CorrectionsOpen Access24 Jan 2023
Nature Food

Volume: 4, P: 191
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
ResearchOpen Access27 Mar 2020
Scientific Reports

Volume: 10, P: 1-11
Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity

Clare E. West
Mohd Karim
Brian D. Marsden
ResearchOpen Access25 Sept 2023
Scientific Data

Volume: 10, P: 1-13
Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
Amendments and CorrectionsOpen Access12 May 2020
Scientific Reports

Volume: 10, P: 1-2

Search

A map of blood regulatory variation in South Africans enables GWAS interpretation

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

Sugar-sweetened beverage intakes among adults between 1990 and 2018 in 185 countries

Children’s and adolescents’ rising animal-source food intakes in 1990–2018 were impacted by age, region, parental education and urbanicity

Global dietary quality in 185 countries from 1990 to 2018 show wide differences by nation, age, education, and urbanicity

Coding and regulatory variants are associated with serum protein levels and disease

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci

Mapping the human genetic architecture of COVID-19

Incident type 2 diabetes attributable to suboptimal diet in 184 countries

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Surface profile analysis of laminated transfemoral prosthetic socket fabricated with different ratios of epoxy resin and acrylic resin

Enhancing shielding efficiency of ordinary and barite concrete in radiation shielding utilizations

Human genetics evidence supports two-thirds of the 2021 FDA-approved drugs

An automated privacy-preserving self-supervised classification of COVID-19 from lung CT scan images minimizing the requirements of large data annotation

Author Correction: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries

Triglyceride to HDL-C Ratio is Associated with Insulin Resistance in Overweight and Obese Children

Multilayer patch functionalized microfibrillated cellulosic paper sensor for sweat glucose monitoring

Employing deep learning and transfer learning for accurate brain tumor detection

CoMOGrad and PHOG: From Computer Vision to Fast and Accurate Protein Tertiary Structure Retrieval

Bootstrapping random forest and CHAID for prediction of white spot disease among shrimp farmers

Validation of a roughness parameters for defining surface roughness of prosthetic polyethylene Pe-Lite liner

Diaporthe species causing stem gray blight of red-fleshed dragon fruit (Hylocereus polyrhizus) in Malaysia

Homalomena pineodora essential oil nanoparticle inhibits diabetic wound pathogens

Processing-Structure-Property Correlation Understanding of Microfibrillated Cellulose Based Dimensional Structures for Ferric Ions Removal

Author Correction: Global dietary quality in 185 countries from 1990 to 2018 show wide differences by nation, age, education, and urbanicity

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Systemic inflammation is associated with incident stroke and heart disease in East Asians

Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity

Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians

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