Nature Search

Natural variation in the promoter of qRBG1/OsBZR5 underlies enhanced rice yield

A rare variation in the promoter of qRBG1/OsBZR5 is associated with larger rice grains. OsBZR5 is found to negatively regulate grain size in rice, a biological role opposite to other OsBZR members. A regulatory module of OsGSK2–qRBG1–OsBZR1–D2–OFP1 is further revealed.

Qiuli Zhang
Renhong Wu
Fangming Zhao
ResearchOpen Access03 Oct 2024
Nature Communications

Volume: 15, P: 1-19
α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex

The role of nicotinic acetylcholine receptors in human cortical development remains largely unexplored. Here authors investigate CHRNA7 and CHRFAM7A, uncovering their involvement in radial glial cell proliferation and neuronal differentiation, and identify YAP1 as a downstream effector of cholinergic signaling.

Tanzila Mukhtar
Clara-Vita Siebert
Arnold R. Kriegstein
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Author Correction: Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils

Xiaochen Wang
Maosheng Cheng
Demeng Chen
Amendments and CorrectionsOpen Access30 May 2025
Nature Communications

Volume: 16, P: 1
Targeting the histone reader ZMYND8 inhibits antiandrogen-induced neuroendocrine tumor transdifferentiation of prostate cancer

Wang et al. reveal that epigenetic changes driven by zinc finger MYND-type containing 8 promote the transition from adenocarcinoma to antiandrogen-resistant neuroendocrine prostate cancer and offer a therapeutic approach by targeting the histone reader with a small molecule.

Hanling Wang
Sulin Zhang
Jun Qin
Research18 Mar 2025
Nature Cancer

Volume: 6, P: 629-646
Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils

Combination immunotherapy with anti-PD-1 and anti-LAG-3 antibodies has shown anti-tumor effects across various cancers, however not all patients respond. Here the authors report that resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by the interaction of Sox9+ tumor cells with Frp1+ neutrophils, resulting in impaired anti-tumor immunity.

Xiaochen Wang
Maosheng Cheng
Demeng Chen
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-20
Publisher Correction: Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers

Baijun Dong
Jun-Yu Xu
Jun Qin
Amendments and Corrections01 Oct 2024
Nature Cancer

Volume: 5, P: 1754
FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC

Transplanted older livers are prone to injury through unclear mechanisms, precluding effective treatment development. Here, the authors show that decreased FTO expression in older livers inhibits Acsl4 and Tfrc mRNA stability in an m6A-dependent manner, increasing cell death in older donor livers.

Rong Li
Xijing Yan
Yang Yang
ResearchOpen Access04 Jun 2024
Nature Communications

Volume: 15, P: 1-20
Molecular and cellular dynamics of the developing human neocortex

Tripotential intermediate progenitor cells are responsible for the local production of GABAergic neurons, oligodendrocyte precursor cells and astrocytes in the human neocortex.

Li Wang
Cheng Wang
Arnold R. Kriegstein
ResearchOpen Access08 Jan 2025
Nature

P: 1-10
Phase behavior of nanoconfined continental shale oil and reservoir fluid phases in the Gulong shale of the Songliao basin

Jiamin Lu
Huasen Zeng
Longde Sun
ResearchOpen Access09 May 2025
Scientific Reports

Volume: 15, P: 1-14
Correlation between ADGRV1 expression and clinical pathological and prognostic features in breast cancer

Lili Wang
Jiadi He
Yuanzhi Lu
ResearchOpen Access05 Jun 2025
Scientific Reports

Volume: 15, P: 1-13
A cross-species proteomic map reveals neoteny of human synapse development

A study presents a cross-species proteomic map of synapse development in neocortex and reveals that the human postsynaptic density assembly develops two to three times slower than that in macaques and mice.

Li Wang
Kaifang Pang
Arnold R. Kriegstein
Research13 Sept 2023
Nature

Volume: 622, P: 112-119
Completing the loop of the Late Jurassic–Early Cretaceous true polar wander event

The authors report three palaeomagnetic poles from the North China craton and document a large round-trip true polar wander oscillation during 155−141 Ma that may have affected biotic evolution in East Asia and global extinction and endemism.

Yifei Hou
Pan Zhao
Rixiang Zhu
ResearchOpen Access12 Mar 2024
Nature Communications

Volume: 15, P: 1-10
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression

The accumulation of myeloid derived suppressor cells (MDSC) has been associated with prostate cancer progression and castration resistance. Here the authors show that loss of ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, results in polymorphonuclear-MDSC infiltration and cooperates with Pten loss to accelerate prostate tumorigenesis.

Ni Li
Qiuli Liu
Jun Qin
ResearchOpen Access26 Nov 2022
Nature Communications

Volume: 13, P: 1-20
A solar wind-derived water reservoir on the Moon hosted by impact glass beads

Analysis of lunar soils sampled by the Chang’e-5 mission suggests that impact glass beads may host a substantial inventory of solar wind-derived water on the Moon’s surface.

Huicun He
Jianglong Ji
Fuyuan Wu
ResearchOpen Access27 Mar 2023
Nature Geoscience

Volume: 16, P: 294-300
Heterodimensional Kondo superlattices with strong anisotropy

The Kondo effect has been observed in transition metal dichalcogenides, where it typically stems from magnetic impurities. Here the authors report the Kondo effect in a heterodimensional superlattice VS₂-VS, where dimensionality effects on intrinsic magnetic properties play a major role.

Qi Feng
Junxi Duan
Yugui Yao
ResearchOpen Access28 Jun 2024
Nature Communications

Volume: 15, P: 1-7
Mettl3-mediated mRNA m⁶A modification controls postnatal liver development by modulating the transcription factor Hnf4a

m⁶A is the most abundant RNA modification of eukaryotic mRNAs and is involved in various physiological and pathological processes. Here the authors show a role for Mettl3-mediated RNA m⁶A modification in postnatal liver development by regulating the Hnf4a-centered transcriptional network

Yan Xu
Zhuowei Zhou
Qi Zhang
ResearchOpen Access05 Aug 2022
Nature Communications

Volume: 13, P: 1-17
Human mesenchymal stromal cells enhance the immunomodulatory function of CD8⁺CD28⁻ regulatory T cells

Qiuli Liu
Haiqing Zheng
Andy Peng Xiang
ResearchOpen Access08 Dec 2014
Cellular & Molecular Immunology

Volume: 12, P: 708-718
Dehydration-induced supralithostatic fluid overpressure in metapelites from Northern Korea

Rapid dehydration and garnet growth can induce supralithostatic fluid overpressure with important implications for tectonic reconstructions and seismic behaviors, according to thermobarometry and geochronology data from Proterozoic metapelites from Northern Korea.

Yi Zou
Xu Chu
Mingguo Zhai
ResearchOpen Access20 Feb 2025
Communications Earth & Environment

Volume: 6, P: 1-11
Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers

Dong et al. present an integrative proteogenomic analysis of high-risk prostate cancer samples from a cohort of Chinese patients and highlight potential therapeutic vulnerabilities and diagnostic markers.

Baijun Dong
Jun-Yu Xu
Jun Qin
Research06 Sept 2024
Nature Cancer

Volume: 5, P: 1427-1447
Dominant Heterogeneity of Upper and Lower Motor Neuron Degeneration to Motor Manifestation of Involved Region in Amyotrophic Lateral Sclerosis

Jiaoting Jin
Fangfang Hu
Jingxia Dang
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-8
Ultrathin graphene oxide-based hollow fiber membranes with brush-like CO₂-philic agent for highly efficient CO₂ capture

Membrane separation technologies show promise for CO₂ capture, but typically suffer from a trade-off between permeance and selectivity. Here, the authors produce hollow fiber membranes coated with graphene oxide and a CO₂-philic agent that can efficiently separate CO₂ from flue gas under wet conditions.

Fanglei Zhou
Huynh Ngoc Tien
Miao Yu
ResearchOpen Access13 Dec 2017
Nature Communications

Volume: 8, P: 1-8
Allogeneic hematopoietic stem cell transplantation overcome the poor prognosis of patients with IKZF1plus CD20–a very high-risk subtype in B-cell acute lymphoblastic leukemia

Bingqing Tang
Zihong Cai
Hongsheng Zhou
Research02 Sept 2022
Bone Marrow Transplantation

Volume: 57, P: 1751-1757
Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction

Kangjunjie Wang
Min Chen
Daming Gao
Research23 Oct 2024
Oncogene

Volume: 44, P: 8-18
Association between oxidative balance score and all-cause mortality in stroke survivors

Jinglin Lei
Zhiyi Liao
Haipeng Li
ResearchOpen Access04 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
The LncRNA lnc-POTEM-4:14 promotes HCC progression by interacting with FOXK1

Bo Peng
Zhipeng Quan
Zeyuan Li
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
From vocation to profession: multiple identities of Chinese management academics

Shubo Liu
Qiuli Huang
Mengna Lv
ResearchOpen Access10 May 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Synthesis, fungicidal activity, structure-activity relationships (SARs) and density functional theory (DFT) studies of novel strobilurin analogues containing arylpyrazole rings

Yuanyuan Liu
Kunzhi Lv
Jinyuan Xu
ResearchOpen Access18 May 2018
Scientific Reports

Volume: 8, P: 1-14
PKC-δ deficiency in B cells displays osteopenia accompanied with upregulation of RANKL expression and osteoclast–osteoblast uncoupling

Shangfu Li
Qiuli Liu
Limin Rong
ResearchOpen Access16 Sept 2020
Cell Death & Disease

Volume: 11, P: 1-17
Single-cell RNA sequencing reveals special basal cells and fibroblasts in idiopathic pulmonary fibrosis

Chengji Jin
Yahong Chen
Huiling Yang
ResearchOpen Access09 Jul 2024
Scientific Reports

Volume: 14, P: 1-14
Light oxygen isotopic composition in deep mantle reveals oceanic crust subduction before 3.3 billion years ago

Subduction may have started as early as 3.3 billion years ago, according to light oxygen isotopes of olivine grains from ancient magmatic rocks of the Barberton Greenstone Belt in Southern Africa which may record the contribution of oceanic crust in the deep mantle

Dongjian Ouyang
Huiming Bao
Qiuli Li
ResearchOpen Access12 Jan 2024
Communications Earth & Environment

Volume: 5, P: 1-9
Stanniocalcin-2 contributes to mesenchymal stromal cells attenuating murine contact hypersensitivity mainly via reducing CD8⁺ Tc1 cells

Xiaoyong Chen
Qiuli Liu
Qi Zhang
ResearchOpen Access10 May 2018
Cell Death & Disease

Volume: 9, P: 1-12
Mesenchymal stem cells alleviate experimental immune-mediated liver injury via chitinase 3-like protein 1-mediated T cell suppression

Qiuli Liu
Xiaoyong Chen
Qi Zhang
ResearchOpen Access04 Mar 2021
Cell Death & Disease

Volume: 12, P: 1-15
Abundant electric-field tunable symmetry-broken states in twisted monolayer-bilayer graphene

Twisted monolayer-bilayer graphene has attracted intense interest due to its rich symmetry-broken states which can be tuned by an external electric field. Here, the authors determine the ground states at half-filling of the conduction band under opposite electric field and report on a symmetry-broken Chern insulator state with its Chern number closely related to the half-filling ground states.

Huimin Peng
Jinrui Zhong
Yugui Yao
ResearchOpen Access15 Jul 2024
Communications Physics

Volume: 7, P: 1-7
Association between baseline office blood pressure level and the incidence and development of long-term frailty in the community-dwelling very elderly with hypertension

Conclusion In community-dwelling very elderly (≥80years) hypertensive patients, the baseline SBP showed a U-shaped curve relationship with the incident and development of long-term frailty, with the inflection points of the U-shaped curve being 135 mmHg and 140 mmHg, respectively, and the baseline PP level showed a U-shaped curve relationship with the development of long-term frailty, with the inflection point of 77 mmHg.

Jin Yan
Bing Wu
Yixin Hu
Research08 Mar 2024
Hypertension Research

Volume: 47, P: 1523-1532
Genome-wide survey indicates diverse physiological roles of the turnip (Brassica rapa var. rapa) calcium-dependent protein kinase genes

Qiuli Wang
Xin Yin
Yongping Yang
ResearchOpen Access17 Nov 2017
Scientific Reports

Volume: 7, P: 1-14
Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT

Qiuli Liu
Dali Tong
Jun Jiang
ResearchOpen Access24 Aug 2017
Cell Death & Disease

Volume: 8, P: e3007
Genetic profiling of hormone-sensitive and castration-resistant prostate cancers and identification of genetic mutations prone to castration-resistant prostate cancer

Ze Wang
Xuzhi Yan
Qiuli Liu
Research18 Nov 2022
Prostate Cancer and Prostatic Diseases

Volume: 26, P: 180-187
Ancient and recent collisions revealed by phosphate minerals in the Chelyabinsk meteorite

Shocked phosphates can record the collisional history of asteroid parent bodies, according to texture-age relationships from microstructural observations and geochronological measurements of apatite and merrillite grains in the Chelyabinsk meteorite

Craig R. Walton
Oliver Shorttle
Mahesh Anand
ResearchOpen Access24 Feb 2022
Communications Earth & Environment

Volume: 3, P: 1-9
Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

Danni Lyu
Lifang Zhang
Ke Yao
ResearchOpen Access01 Oct 2021
npj Regenerative Medicine

Volume: 6, P: 1-14
α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis

Kuo Liu
Ya Liu
Shaojun Wen
Research13 Jan 2011
Hypertension Research

Volume: 34, P: 389-399
Construction of a Corneal Stromal Equivalent with SMILE-Derived Lenticules and Fibrin Glue

Houfa Yin
Peijin Qiu
Yabo Yang
ResearchOpen Access21 Sept 2016
Scientific Reports

Volume: 6, P: 1-10
Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans

Ziheng Zhuang
Min Li
Dayong Wang
ResearchOpen Access30 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
In vitro molecular evolution yields an NEIBM with a potential novel IgG binding property

Peipei Qi
Ying-Ying Ding
Wei Pan
ResearchOpen Access04 Nov 2014
Scientific Reports

Volume: 4, P: 1-9
Association between the angiotensinogen gene T174M polymorphism and hypertension risk in the Chinese population: a meta-analysis

Wei Gu
Ya Liu
Shaojun Wen
Research01 Sept 2011
Hypertension Research

Volume: 35, P: 70-76
The kinase AKT1 potentiates the suppressive functions of myeloid-derived suppressor cells in inflammation and cancer

Anna Jia
Yuexin Wang
Guangwei Liu
Correspondence18 Jan 2021
Cellular & Molecular Immunology

Volume: 18, P: 1074-1076
Crucial role of histone deacetylase SIRT1 in myeloid-derived suppressor cell-mediated reprogramming of CD4⁺ T-cell differentiation

Lin Dong
Yujing Bi
Guangwei Liu
Correspondence07 Apr 2020
Cellular & Molecular Immunology

Volume: 17, P: 785-787

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