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This work demonstrates that epitaxial match at the oxide-support interfaces plays a critical role in determining whether supported metal nanoparticles oxidize from the interface or the free surface in oxygen, thereby enabling controlled oxidation.

Genomic imprinting, manifested as monoallelic expression of genes according to parental origin, is linked to mammalian placentation and human diseases. The authors integrate single-nucleus transcriptomes and whole-genome variations to create a cell type-specific genomic imprinting atlas of pig placenta, highlighting the role of cell-cell communication in parent-of-origin effects on gene expression.

Interpreting bone metastases (BMs) from computed tomography (CT) images remains challenging. Here, the authors develop an AI-based Bone Lesion Detection System - BLDS - and validate it in a cohort of 2,518 patients across five hospitals, showing highly sensitive and accurate performance for BM detection from CT scans.

Construction of a phosphate passivation layer on the surface of a cathode to withstand fluctuating operation in alkaline seawater is proposed following understanding the mechanism behind the dynamic evolution and degradation of cathode in intermittent electrolysis.

A crystal with giant birefringence in the visible and infrared could benefit applications that rely on manipulating optical polarization.

Fabricating geometrically complex piezoceramics in compact sintered bodies has been difficult to achieve. Here the authors demonstrate a gravity-driven sintering strategy where high-temperature viscous behavior of piezoceramic allows for forming of complex shaped sintered bodies.

The poor structural stability of cathode materials is responsible for the rapid capacity loss of sodium-ion batteries during cycling. This work addresses the instability by introducing vacancies into the transition metal layers and realize long-life pouch cells.

There is a critical crack thickness in the production of thin films. Here, the authors utilize the surface tension of the liquid to eliminate the stresses within the film and produce ceramic layers with a controllable thickness and shape.

A three-photon miniature microscope with optimized light-collection efficiency facilitates imaging of neuronal activity throughout the cortex, as well as in the hippocampus, in freely moving mice.

Wang et al. profile the translatome of haematopoietic stem cells (HSCs) and downstream progenitors and lineages. They identify the SNORD113–114 cluster as a modulator of translation and self-renewal in HSCs.

Three-dimensional architecture engineering allows for higher performance ceramics with more diverse applications. Here, the authors report a simple and efficient manufacturing process for cellular ceramics in programmed cell-based 3D configurations.

The invasiveness of extensive craniotomy hinders large-scale cortex mapping. Here, the authors developed a flexible, shape-changing electrode array which enables minimally invasive implantation and achieves high spatiotemporal resolution brain mapping.

Here, the authors use multi-omic data to reveal how genetic and epigenetic variation affects gene expression in two pig breeds. The findings highlight strong tissue-specific regulation and identify genes with allele-specific expression.

Piezoelectric biomaterials are limited by the challenges in ___domain orientation alignment and a weak piezoelectric effect. Here, Zhang et. al. present an active self-assembly strategy via nanoconfinement and in-situ poling, to obtain large-scale, high performance piezoelectric β-glycine nanocrystalline films.

Layered oxide cathode materials for sodium-ion batteries often experience irreversible phase transitions and structural instability. Now researchers have developed a P2-type oxide containing earth-abundant elements, featuring an intergrowth phase structure that enables long-cycle, high-energy sodium-ion batteries.

Shaping ceramics is important for realizing their material properties. Here, the authors modify a Joule heating method to generate morphing thermomechanical fields, guiding the shape formation of ceramics into complex 3D configurations.

Many solid microstructures have limited sensitivity over a wide pressure range due to their inherent structural compressibility. Xiong et al. propose a Marangoni-driven deterministic formation approach for creating hollow microstructures, enabling greater deformation while hindering structural stiffening.

Nanocrystalline metallic materials have the merit of high strength, but usually suffer from poor ductility and rapid grain coarsening. Here, the authors develop a nanocrystalline core-shell alloy to overcome these challenges.

Deng et al. report a charge-assisted oriented assembly for wafer-scale film formation of 2D perovskite oxide nanosheets. An ultra-flexible 256-pixel photodetector array enables conformal imaging capability and achieves high-accuracy motion recognition with the convolutional neural network.

Oocyte meiotic defects increase with age and contribute to decreased oocyte quality. Here the authors show that granulosa cell mevalonate pathway abnormalities contribute to aneuploidy during ovarian aging and that supplementation with mevalonate metabolites improves oocyte quality, providing a potential therapeutic strategy for promoting female reproductive longevity.

Functional divergence of CYP76AK subfamily, accompanied by oxidation variations at C-20, leads to diverse abietane-type diterpenoids in Salvia species. Enzyme activity loss contributes to this unique chemical diversity within the lineage.

ABA signaling and Ca²⁺ signaling regulatory networks are crucial for how plants respond to drought stress. Here, the authors reported that the functional module of the CBL1/9-CIPK1-PYLs regulatory network plays a negative role in ABA signaling and its response to drought stress.

In this work, authors demonstrate a fast and versatile microprinting technique to produce high-performance and customizable piezoelectric elements by employing a conductive spiny disc to electrostatically trigger instability to the liquid-air interface of the ink.

The prime editors (PEs) have shown great promise for precise genome modification. Here the authors place a stabilizing viral xrRNA motif to the 3′ of pegRNAs to enhance editing efficiencies.

Blind and partially sighted individuals face considerable challenges when interacting with digital information. This Perspective highlights important bottlenecks in information accessibility, design considerations for future wearable assistive devices and the outlook for improved access to and delivery of information in text and images.

High-density, intrinsically stretchable transistors with high driving ability and integrated circuits with high operation speed and large-scale integration were enabled by a combination of innovations in materials, fabrication process design, device engineering and circuit design.

Mediator subunit MED26 was shown to help recruit Super Elongation Complex (SEC) or Little Elongation Complex (LEC) to control the expression of certain genes. Here, the authors provide evidence that MED26 recruits LEC to regulate transcription termination of non-polyadenylated genes, including snRNA and replication-dependent histone (RDH) genes at Cajal bodies.

Atomically thin chromium tri-iodide is shown to be a 2D ferromagnetic insulator with an optical response dominated by ligand-field transitions, emitting circularly polarized photoluminescence with a helicity determined by the magnetization direction.

Statins have anti-cancer effects that are modulated by the gut commensal Lactobacillus reuteri and the tryptophan metabolite, indole-3-lactic acid, in mice and humans.

By isolating one-dimensional tellurium nanowires in boron nitride nanotubes, the electronic properties of the atomic chains can be measured and the structures used to create field-effect transistors.

Solid–liquid interfaces are ubiquitous in natural and technological processes, but their imaging at the atomic scale has been challenging. The authors, using liquid-phase transmission electron microscopy, identify a quasi-liquid phase and the mass transport between the surface of In and Sn nanocrystals and an aqueous solution.

A two-photon miniature microscope with enlarged field of view and axial scanning capabilities has been developed and applied in freely moving mice.

Gao et al. show that a secretory variant of E-cadherin encoded by a circular RNA directly activates EGFR and STAT3 signalling, thereby promoting glioma stem cell tumorigenicity.