This paper defines the role of the protein autophagy-related 7 (Atg7) in triple-negative breast cancer (TNBC). Atg7 inhibits proliferation and migration, and promotes apoptosis of TNBC cells. Furthermore, Atg7 prevents epithelial-mesenchymal transition through downregulation of aerobic glycolysis. Atg7 is therefore a potential prognostic marker and therapeutic target for TNBC.
- Mingyang Li
- Jingwei Liu
- Liu Cao
