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Some rhizosphere microbes protect plants from phytopathogens through unclear molecular mechanisms. Here, Zhang et al. show that a rhizosphere bacterium displays antimicrobial activity against phytopathogenic fungi by reducing the activity of the fungal NatA acetyltransferase complex, thus inducing protein degradation and apoptosis.

The growth of Li dendrites and the accumulation of dead Li significantly undermine the safety and performance of Li metal batteries. Here, authors introduce the concept of “catalytic” effect for dead Li reconversion, leading to a Li plating/stripping efficiency of 99.89%.

Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing surface protein expression across large and heterogeneous datasets.

A versatile nano-adaptor is used to construct multi-specific nano-antibodies for treatment of tumours in mice.

Urothelial bladder cancer (UC) progression occurs as a multi-step process that leads to different kinds of lesions and subtypes. Here, the authors characterise benign and invasive lesions that occur during UC progression using proteogenomics in patient samples and show critical molecular pathways and prognostic associations.

Targeted deletion of integrin-associated protein CD47 enhances long-term engraftment of human CD34⁺ cells in immunodeficient pigs lacking IL2RG and RAG2, enabling large-scale production of functional human immune cells.

Electrocardiogram is crucial for cardiovascular disease prevention, diagnosis, and prognosis. Here, the authors present a motion-unrestricted dynamic electrocardiogram system utilizing skin-conformal, imperceptible electronics for long-term, comfortable, and accurate 12-lead monitoring.

Scaling effects on ferroelectric domains could impact applications for next-generation miniaturized devices. Here brownmillerite oxides are shown to demonstrate ferroelectric domains with widths down to the sub-unit-cell level.

Gold redox catalysis is an attractive synthetic method but challenging due to the high redox potential of Au(I)/Au(III). Now, a bidentate N-ligand-assisted gold redox catalysis using H₂O₂ as oxidant has been developed. It can be applied to various coupling reactions, including C(sp)–C(sp) cross-coupling, alkynylative cyclization and bicyclization coupling.

Base editing of the pathogenic trinucleotide repeat expansions underlying Huntington’s disease and Friedreich’s ataxia introduces repeat interruptions that reduce somatic expansion in patient cells and mice.

Toxic chemicals can transform in the environment, often forming more harmful products. This study provides evidence for the aqueous formation of organophosphate esters (OPEs) in aerosols, highlighting their fate and implications for risk assessment.

Liquid-phase hydrogenation of nitroarenes is a key industrial process, but conventional supported metal nanoparticles often suffer deactivation in the presence of sulfur-containing groups. Here, the authors design a dual-site Pt/CeO₂ catalyst that enables selective hydrogenation of S-nitroarenes by separating catalytic roles.

Long-range interactions in many-body quantum systems may induce dissipation channels described by non-Hermitian dynamics. Here, the authors report the observation of higher-order exceptional points, a hallmark of non-Hermitian physics, in a Rydberg atom gas. This enables design of quantum dynamics around these points, providing insight into phase transitions.

Friction and wear cause widespread energy loss and damage. Here, the authors propose a strategy to reduce friction and wear through inducing dynamic electronic density redistribution via alternating electric current.

Domestication of crops has boosted food production but increased dependence on fertilizers and pesticides. This study shows that wild rice harbors a higher abundance of nitrogen-fixing genes in the rhizosphere, while domesticated rice has more genes associated with nitrous oxide production.

Continuous shape morphing for small robots can offer advantages, but it is difficult to perform tasks if they are not stiff enough. Xu et al. present here a design combining liquid crystal elastomers and shape memory polymers to lock morphable elements in place.

Insights into how the linker histone H1 promotes chromatin alterations and allows repair of DNA damage are described.

This study provides insights into how shade induces leaf senescence in soybean. The reduction of blue light intensity deactivates GmCRY1s, leading to the degradation of GmRGAs and the upregulation of WRKY100, ultimately promoting leaf senescence.

Heterogeneous single-atom catalysts (SACs) offer high atom utilization and well-defined active sites but face challenges in multi-stage cross-couplings due to limited coordination and reactivity. Here, the authors introduce SACs on reducible carriers, enabling adaptive coordination to bypass oxidative addition in cross-couplings.

A plant kinase mediates symbiotic signalling and suppress host immunity to enable legume–rhizobium symbiosis.

Cross-phase manipulation holds potential for applications in synthetic biology and drug delivery. Here, authors present an acoustofluidic platform that enables rapid embedding of microparticles from an oil phase into aqueous droplets, offering an effective tool for studying cellular multiphase interactions and related phenomena.

Risk factors modification is crucial for diabetes care. Here, the authors show the relationships of combined modifiable risk factors with common complications of type 2 diabetes and provide further insights into the mediating role of plasma proteomics.

A size-sieved complex precipitation in Sc-added Al–Mg alloys achieves a high-density dispersion of both fine Al₃Sc nanoprecipitates and in situ formed core-shell Al₃(Mg, Sc)₂/Al₃Sc nanophases with high hydrogen-trapping ability.

ABA signaling is found to modulate global mRNA translation efficiency. GRP7 associates with ribosomes and directly binds to its target mRNAs. ABA suppresses GRP7&8 protein levels via its core signaling components and decreases global mRNA translation efficiency.

Exotic chiral fermions beyond Weyl fermions have recently been discovered in a series of chiral crystals such as CoSi. Here, the authors report the evidences of chiral fermions in RhSn with opposite handedness compared to those observed in CoSi, where the structural chirality is also opposite.

Achieving sustainability in wireless communications is crucial yet poses significant challenges. To address this, the authors propose and demonstrate a solar-powered programmable metasurface enabling hybrid light-to-microwave wireless communications.

The elastic limit represents the maximum stress and strain a material can withstand and is well characterized in many crystalline solids, yet remains elusive for metallic glasses. Here, this limit is investigated in submicron metallic glass structures and is found to be twice as high as that of bulk samples.

Worldwide, the number of only-child families is increasing. This research examines how growing up without siblings affects adult brain structure, function and connectivity, cognition, personality and mental health.

Molecular assembly is of great importance in many fields. Here, the authors establish a strategy to post-modulate angle-mismatched layer-by-layer materials by fullerene derivatives and achieve a modulation accuracy of up to 5 Å.

Reactive capture—integrating CO₂ capture and electrochemical valorization—improves energy efficiency by eliminating gas-phase CO₂ desorption. Here, authors design a redox-active polymeric network to boost the direct conversion of captured CO₂ to multicarbon products with CO₂-free gas product stream.

The authors reveal a complex polarization network in twisted bilayer h-BN, featuring edge polarization topology and sliding ferroelectricity, driven by the interplay of ferroelectric and piezoelectric effects.

The search for lunar polycyclic aromatics is challenging. Here abundance, aromatic structures and carbon isotope composition of polycyclic aromatics in Chang’E 5 lunar soils are reported, shedding light on the fate of polycyclic aromatics and accretion of organic carbon on the Moon.

Glycosylated asparagine residues that mediate the function of the B7H3 protein are unclear. Here the authors identify the important N-glycosylation sites for B7H3 cell surface localization and T cell inhibition, followed by the development of N91/309 and N104/322 preferentially targeting monoclonal antibody manifesting enhanced antitumor immunity.

Liu and colleagues examine how severe acute respiratory syndrome coronavirus 2 variants evade CD8⁺ T cell epitope recognition.

Echinacoside (ECH) is the representative phenylethanoid glycosides (PhGs) that are responsible for the bioactivities of traditional Chinese medicine Cistanche Herba. Here, the authors elucidate the biosynthetic pathway of ECH in Cistanche tubulosa and synthesize 23 PhGs in tobacco.

The study revealed how nitrogen fertilization affects fast and slow turnover pools of soil organic carbon differently. The authors found labile particulate organic carbon increased if SOC was below 1.5%, while stable mineral associated organic carbon increased above this critical threshold.

Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce generalised seizures.

This study uncovers a unique broad neutralization mechanism against rotavirus, where antibody 7H13 destabilizes the partial structure of the viral VP4 spike by acting on a critical residue switch located at the interface of multiple VP4 subunits.

The authors present a valley-Hall topological acoustofluidic chip revealing the complex interactions between elastic valley spin and nonlinear fluid dynamics, revealing its potential towards on-chip biological applications.